Genetic Engineering

Bacterial adhesion at the single-cell level

Review Article | Published: 15 July 2018<p>Cecile Berne ORCID: orcid.org/0000-0003-3731-9317,<br>• Courtney K. Ellison ORCID: …

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The downfall of Theranos, from the journalist who made it happen

John Carreyrou's book is a look at the chaos and conniving behind the scenes.<p>Over the last few years, the failed biomedical startup Theranos has …

Silicon Valley

Gene editing gets a head start

The development of gene-editing technologies into therapies for human disease is an exciting prospect. A crucial question is whether there are …

Genetics

Uttar Pradesh: Tested positive for HIV, man, two daughters commit suicide

According to neighbours, the deceased man was HIV-positive and his wife, who died a few years back, had also tested positive for the same.<p>By: |<p>A man …

Uttar Pradesh

Is Inpatient Volume Or Emergency Department Crowding A Greater Driver Of Ambulance Diversion?

1 Lee YJ, Shin SD, Lee EJ, Cho JS, Cha WC. Emergency department overcrowding and ambulance turnaround time. PLoS One. 2015;10(6):e0130758.Crossref, …

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Scientists Just Found a Novel, Cheap Way to Use CRISPR Gene Editing to Fight Cancer

CRISPR is by all accounts a fascinating technology. Its headline feature is that it can literally be used to slice, dice, and otherwise manipulate …

Molecular Biology

Reprogramming human T cell function and specificity with non-viral genome targeting

Letter | Published: 11 July 2018<p>Theodore L. Roth,<br>• Cristina Puig-Saus,<br>• Ruby Yu,<br>• Eric Shifrut,<br>• Julia Carnevale,<br>• P. Jonathan Li,<br>• Joseph Hiatt,<br>• Justin …

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Geographic Variation in Larval Metabolic Rate Between Northern and Southern Populations of the Invasive Gypsy Moth | Journal of Insect Science

Thermal regimes can diverge considerably across the geographic range of a species, and accordingly, populations can vary in their response to …

Google Scholar

CRISPR's growing pains

In the six years since its inception, CRISPR gene editing has experienced ups and downs, from giddy excitement over the technology's potential to …

CRISPR

Howard County family provides support for sickle cell disease patients

Growing up, Mikaili and Khari Robertson often felt different from other kids.They kept gallon-sized water jugs sitting by their desks at school, …

Genetic Engineering

Swift Gene-Editing Method May Revolutionize Treatments for Cancer and Infectious Diseases

For the first time, scientists have found a way to efficiently and precisely remove genes from white blood cells of the immune system and to insert beneficial replacements, all in far less time than it normally takes to edit genes.<p>If the technique can be replicated in other labs, experts said, it …

Bioethics

What Does a Positive Herpes IgM Test Result Mean?

What is a Herpes IgM Test?<p>A herpes IgM test is a type of blood test that can be used to detect an early herpes herpes (HSV) infection. This test does …

Molecular Biology

T cell engineering breakthrough sidesteps need for viruses in gene-editing: With faster, cheaper, more precise technique, authors say it's 'off to the races' toward new cell therapies

With faster, cheaper, more precise technique, authors say it's 'off to the races' toward new cell therapies<p>In an achievement that has significant …

Genetics

Epigenetic regulation in development: is the mouse a good model for the human? | Human Reproduction Update

BACKGROUND<p>Over the past few years, advances in molecular technologies have allowed unprecedented mapping of epigenetic modifications in gametes and …

Genetics

Will 'Holmes and Holmes' Stars Mike Jr. & Lisa Find a Wedding Venue? (VIDEO)

The DIY show will also feature many other wedding moments this season.

Weddings

Intracytoplasmic sperm injection for male infertility and consequences for offspring | Nature Reviews Urology

Review Article | Published: 02 July 2018<p>Intracytoplasmic sperm injection for male infertility and consequences for offspring<p>Sandro C. Esteves ORCID: …

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Gene edited monkeys offer hope for heart disease patients

For the first time, researchers have used gene-editing tools in adult monkeys to disable a gene throughout much of the liver. The approach lowered …

Genetics

Baltimore biotech Elixirgen Therapeutics making drugs to target rare diseases, raises $4 million - Baltimore Business Journal

By Morgan Eichensehr <br>– Reporter, Baltimore Business Journal<p>Jul 9, 2018, 8:45am EDT<p>A Baltimore biotechnology company has raised $4 million, to help …

Baltimore

Bad Blood: Secrets and Lies in a Silicon Valley Startup, by John Carreyrou | Financial Times

<i>Bad Blood</i> is already out of date. Subsequent editions of this riveting story, which recounts the implosion of Theranos, the disgraced blood-testing …

Silicon Valley

Here's Why CRISPR Therapeutics AG Fell 14.7% in June

Investors began paying closer attention to the results from two studies suggesting a link between certain gene-editing tools and cancer.<p>What …

Investing

HLA in transplantation

Review Article | Published: 09 July 2018<p>Robert A. Montgomery,<br>• Vasishta S. Tatapudi,<br>• Mary S. Leffell &<br>• Andrea A. Zachary<p><i>Nature Reviews Nephrology</i> (2018) …

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Gene-editing technique cures genetic disorder in utero

Carnegie Mellon and Yale study in mice shows promise for treating genetic conditions during early stages of development<p>Researchers at Carnegie Mellon …

Genetics

Genome editing reduces cholesterol in large animal model, laying human trial groundwork

Using genome editing to inactivate a protein called PCSK9 effectively reduces cholesterol levels in rhesus macaques, a species of monkey, according …

University of Pennsylvania

Towards simple kinetic models of functional dynamics for a kinase subfamily

Article | Published: 09 July 2018<p>Mohammad M. Sultan,<br>• Gert Kiss &<br>• Vijay S. Pande ORCID: orcid.org/0000-0003-2774-1178<p><i>Nature Chemistry</i> (2018) | Download …

Google Scholar

Theranos founder’s false promises offer a lesson

LESS than three months after being charged by the US Securities and Exchange Commission (SEC) with “massive fraud” and barred from being the CEO of a …

News (China)

From Gene-Editing Cures to Bioweapon Nightmare

Crispr has driven biotech investment, but also the possibility of dangerous applications.<p>The latest biotech investment craze runs on excitement over Crispr, a technique for making gene editing easier and more precise, which biologists have already used to remove disease-causing genes from human …

Genetics

Protein’s novel role in embryo implantation studied

A large number of couples are infertile and in many cases IVF is not successful and there are repeated failures. In a latest development, …

Molecular Biology

Guest editorial: Trust the facts on genetically engineered foods (Bloomberg)

<i>Editor’s note: This editorial was published by Bloomberg Opinion.</i><p>The U.S. Department of Agriculture has come up with cheerful new labels for …

Biomedical Engineering

Scientists reprogram T Cells to target autoimmune diseases

Researchers from the University of San Francisco have uncovered a gene-editing technique which could provide safer treatments for patients with cancer and autoimmune diseases. The breakthrough -- which involves the CRISPR/Cas9 system -- will allow T cells (the cells which fire up our immune …

Immunotherapy

Experimental HIV Vaccine Shows Promise in Early Trial

FRIDAY, July 6, 2018 (HealthDay News) -- An experimental HIV vaccine was safe and triggered strong immune responses in healthy adults and in monkeys, …

Public Health