JMSadded this to Science AddictionMalaria Plasmodium vivax chloroquine resistance links to pvcrt transcription inature.com - Juliana M. Sá, Sarah R. Kaslow, Roberto R. Moraes Barros, Nicholas F. Brazeau, Christian M. Parobek, Dingyin Tao, Rebecca E. Salzman, Tyler J. Gibson, Soundarapandian Velmurugan, Michael A. Krause, Viviana Melendez-Muniz, Whitney A. Kite, Paul K. Han, Richard T. Eastman, Adam Kim, Evan G. Kessler, Yonas Abebe, Eric R. James, Sumana Chakravarty, Sachy Orr-Gonzalez, Lynn E. Lambert, Theresa Engels, Marvin L. Thomas, Pius S. Fasinu, David Serre, Robert W. Gwadz, Larry Walker, Derrick K. DeConti, Jianbing Mu, Jeffrey A. Bailey, B. Kim Lee Sim, Stephen L. Hoffman, Michael P. Fay, Rhoel R. Dinglasan, Jonathan J. Juliano, Thomas E. Wellems Battle, K. E. et al. Mapping the global endemicity and clinical burden of Plasmodium vivax, 2000–17: a spatial and temporal modelling study. Lancet 394, …
All That's Interestingadded this to ATI News RoomNeanderthals Scientists Reveal What Our Denisovan Ancestors Looked Like 75,000 Years Agoallthatsinteresting.com - Natasha Ishak When scientists first discovered these remains of a teenage girl in 2010, they knew that the history of early humans was about to be rewritten. Now …
Wayne Neumannadded this to MScience108Biology Extinct Denisovan Woman Gets Her First Portrait Thanks to DNA from Her Pinky BoneLive Science - Brandon Specktor As recently as 15,000 years ago, humans shared their caves with another group of upright apes called the Denisovans. The two hominins were …
Protein Segregation and potential functional impact of a rare stop-gain PABPC4nature.com - Muhammad Aslam, Anwar Ullah, Nagarajan Paramasivam, Nirosiya Kandasamy, Saima Naureen, Mazhar Badshah, Kafaitullah Khan, Muhammad Wajid, Rashda Abbasi, Roland Eils, Marc A. Brockmann, Matthias Schlesner, Nafees Ahmad, Jakob von Engelhardt Stamelou, M., Quinn, N. P. & Bhatia, K. P. ‘Atypical’ atypical parkinsonism: New genetic conditions presenting with features of progressive …
IKITOadded this to Healthy LivingDNA Key similarities discovered between human and archaea chromosomes | EurekAlert! Science Newseurekalert.org Discovery from Indiana University could advance use of single-celled organism in research on cancers related to errors in cellular gene expression A …
Diane Siburtadded this to BearsScience Grizzlies show remarkable gene control before and during hibernationphys.org - Charlie Powell Being a human couch potato can greatly increase fat accumulation, hasten the onset of Type II diabetes symptoms, result in detrimental blood …
Genetics Multi-view based integrative analysis of gene expression data for idennature.com - Zi-Yi Yang, Xiao-Ying Liu, Jun Shu, Hui Zhang, Yan-Qiong Ren, Zong-Ben Xu, Yong Liang The widespread applications in microarray technology have produced the vast quantity of publicly available gene expression datasets. However, …
rye_breadadded this to ADHD Brain DrainGenes Comparative evaluation of RNA-Seq library preparation methods for stranature.com - Dimitra Sarantopoulou, Soon Yew Tang, Emanuela Ricciotti, Nicholas F. Lahens, Damien Lekkas, Jonathan Schug, Xiaofeng S. Guo, Georgios K. Paschos, Garret A. FitzGerald, Allan I. Pack, Gregory R. Grant Library preparation is a key step in sequencing. For RNA sequencing there are advantages to both strand specificity and working with minute starting …
Breast Cancer Epigenetic re-wiring of breast cancer by pharmacological targeting ofnature.com - Jung S. Byun, Samson Park, Dae Ik Yi, Jee-Hye Shin, Sara Gil Hernandez, Stephen M. Hewitt, Marc C. Nicklaus, Megan L. Peach, Laura Guasch, Binwu Tang, Lalage M. Wakefield, Tingfen Yan, Ambar Caban, Alana Jones, Mohamed Kabbout, Nasreen Vohra, Anna María Nápoles, Sandeep Singhal, Ryan Yancey, Adriana De Siervi, Kevin Gardner Boyd, J. M. et al. A region in the C-terminus of adenovirus 2/5 E1a protein is required for association with a cellular phosphoprotein and important …
Rehan Qayyumadded this to Dr. Q's Clinical MedicineLymphoma A novel lymphoma-associated macrophage interaction signature (LAMIS) pnature.com - Annette M. Staiger, Michael Altenbuchinger, Marita Ziepert, Christian Kohler, Heike Horn, Michael Huttner, Katrin S. Hüttl, Gunther Glehr, Wolfram Klapper, Monika Szczepanowski, Julia Richter, Harald Stein, Alfred C. Feller, Peter Möller, Martin-Leo Hansmann, Viola Poeschel, Gerhard Held, Markus Loeffler, Norbert Schmitz, Lorenz Trümper, Tobias Pukrop, Andreas Rosenwald, German Ott, Rainer Spang Swerdlow SH, Campo E, Harris NL, Jaffe ES, Pileri SA, Stein H, et al. WHO classification of tumours of haematopoietic and lymphoid tissues. 4th ed. …
Liver Spatial sorting enables comprehensive characterization of liver zonatinature.com - Shani Ben-Moshe, Yonatan Shapira, Andreas E. Moor, Rita Manco, Tamar Veg, Keren Bahar Halpern, Shalev Itzkovitz Hoehme, S. et al. Prediction and validation of cell alignment along microvessels as order principle to restore tissue architecture in liver …
Full Nameadded this to Immunology & Pathogens E.coli Measuring transcription at a single gene copy reveals hidden drivers onature.com - Mengyu Wang, Jing Zhang, Heng Xu, Ido Golding Sanchez, A. & Golding, I. Genetic determinants and cellular constraints in noisy gene expression. Science 342, 1188–1193 (2013). Golding, I. et al. …
Genetics A repeated molecular architecture across thalamic pathwaysnature.com - James W. Phillips, Anton Schulmann, Erina Hara, Johan Winnubst, Chenghao Liu, Vera Valakh, Lihua Wang, Brenda C. Shields, Wyatt Korff, Jayaram Chandrashekar, Andrew L. Lemire, Brett Mensh, Joshua T. Dudman, Sacha B. Nelson, Adam W. Hantman Sherman, S. M. & Guillery, R. W. The role of the thalamus in the flow of information to the cortex. Philos. Trans. R. Soc. B Biol. Sci. 357, 1695–1708 …
Towards Data Scienceadded this to Machine LearningProtein Integrative analysis of single-cell multi-omics data using deep learningtowardsdatascience.com - Yuan Tian Single-cell RNA sequencing (scRNA-seq) has offered a comprehensive and unbiased approach to profile immune cells including T cells with a single-cell …
Protein The redox metabolic pathways function to limit Anaplasma phagocytophilnature.com - Pilar Alberdi, Alejandro Cabezas-Cruz, Pedro Espinosa Prados, Margarita Villar Rayo, Sara Artigas-Jerónimo, José de la Fuente Novo, E. & Parola, M. Redox mechanisms in hepatic chronic wound healing and fibrogenesis. Fibrogenesis Tissue Repair. 1, 5 (2008). Marchi, S. et al. …
Potatoes Transcriptome analysis of Globodera pallida from the susceptible hostnature.com - Rinu Kooliyottil, Louise-Marie Dandurand, Joseph C. Kuhl, Allan Caplan, Fangming Xiao, Benjamin Mimee, Joël Lafond-Lapalme Nicol, J. M. et al. Current nematode threats to world agriculture. In: Genomics and Molecular Genetics of Plant-Nematode Interactions (Eds Jones, J. …
Prostate Suitability of ultrasound-guided fine-needle aspiration biopsy for tranature.com - H. Thiemeyer, L. Taher, J. T. Schille, L. Harder, S. O. Hungerbuehler, R. Mischke, M. Hewicker-Trautwein, Z. Kiełbowicz, B. Brenig, E. Schütz, J. Beck, H. Murua Escobar, I. Nolte Alonge, S., Melandri, M., Aiudi, G. & Lacalandra, G. M. Advances in prostatic diagnostics in dogs: The role of Canine Prostatic Specific Esterase …
Genetics Metabolomic and gene expression approaches reveal the developmental annature.com - Guillermo F. Padilla-González, Maximilian Frey, Javier Gómez-Zeledón, Fernando B. Da Costa, Otmar Spring Turner, B. L. Fossil history and geography. In The Biology and Chemistry of the Compositae vol. 1 (eds Heywood, V. H., Harborne, J. B. & Turner, B. L.) …
Dave Gardneradded this to Honeybees & Beekeepers, Information.Science Study shows bee brains process positive and negative experiences differentlyphys.org - Bob Yirka A team of researchers at the University of Illinois at Urbana-Champaign has found that when bees experience positive versus negative events, their …
rye_breadadded this to ADHD Brain DrainMicrobiome An Experimental Approach to Rigorously Assess Paneth Cell α-Defennature.com - Patricia A. Castillo, Eric B. Nonnecke, Daniel T. Ossorio, Michelle T. N. Tran, Stephanie M. Goley, Bo Lönnerdal, Mark A. Underwood, Charles L. Bevins Peterson, L. W. & Artis, D. Intestinal epithelial cells: regulators of barrier function and immune homeostasis. Nat Rev Immunol 14, 141–153 (2014). Ley, …
Methylation Transgenerational Self-Reconstruction of Disrupted Chromatin Organizatnature.com - Carlos Diaz-Castillo, Raquel Chamorro-Garcia, Toshi Shioda, Bruce Blumberg Hales, C. M., Carroll, M. D., Fryar, C. D. & Ogden, C. L. Prevalence of Obesity Among Adults and Youth: United States, 2015–2016. NCHS Data Brief, …
Asthma NeTFactor, a framework for identifying transcriptional regulators of gnature.com - Mehmet Eren Ahsen, Yoojin Chun, Alexander Grishin, Galina Grishina, Gustavo Stolovitzky, Gaurav Pandey, Supinda Bunyavanich Ozsolak, F. & Milos, P. M. RNA sequencing: advances, challenges and opportunities. Nat Rev Genet 12, 87–98 (2011). Libbrecht, M. W. & Noble, W. S. …
Protein Study explores role of mediator protein complex in transcription and gene expression | EurekAlert! Science Newseurekalert.org - www.eurekalert.org Did you know that the DNA in any cell of the human body - or any organism for that matter - contains the genetic information required to develop …
High-Definition High-definition spatial transcriptomics for in situ tissue profilingnature.com - www.nature.com A dense, spatially barcoded bead array captures RNA from histological tissue sections for spatially resolved gene expression analysis.
Bioinformatics Immediate and deferred epigenomic signatures of in vivo neuronal activnature.com - Jordi Fernandez-Albert, Michal Lipinski, María T. Lopez-Cascales, M. Jordan Rowley, Ana M. Martin-Gonzalez, Beatriz del Blanco, Victor G. Corces, Angel Barco Yap, E. L. & Greenberg, M. E. Activity-regulated transcription: bridging the gap between neural activity and behavior. Neuron 100, 330–348 …
Icon version of the Flipboard logoBiology Fig. 1 | npj Systems Biology and Applicationsnature.com - www.nature.com Schematic view of the proteome allocation problem. a Effect of growth limitation via carbon starvation on proteome composition. An increase in the …
George Seblonkaadded this to StuffCancer pathCHEMO, a generalizable computational framework uncovers molecularnature.com - Nusrat J. Epsi, Sukanya Panja, Sharon R. Pine, Antonina Mitrofanova Siegel, R. L., Miller, K. D. & Jemal, A. Cancer statistics, 2017. CA: a cancer J. Clin. 67, 7–30 (2017). Pfister, D. G. et al. American Society of …
E.coli Gene networks that compensate for crosstalk with crosstalknature.com - Isaak E. Müller, Jacob R. Rubens, Tomi Jun, Daniel Graham, Ramnik Xavier, Timothy K. Lu Capra, E. J., Perchuk, B. S., Skerker, J. M. & Laub, M. T. Adaptive mutations that prevent crosstalk enable the expansion of paralogous signaling …
The Brain How do we get so many different types of neurons in our brain? | EurekAlert! Science Newseurekalert.org - www.eurekalert.org New SMU study may provide insight on how our brains are able to produce so many different types of neurons, which control everything we do DALLAS …
Leukemia Oncogenic heterogeneous nuclear ribonucleoprotein D-like modulates thenature.com - Dehuan Ji, Pengshan Zhang, Wenjuan Ma, Yiwen Fei, Wen Xue, Yu Wang, Xiuyan Zhang, Haixia Zhou, Yun Zhao Dreyfuss G, Matunis MJ, Piñol-Roma S, Burd CG. hnRNP proteins and the biogenesis of mRNA. Annu Rev Biochem. 1993;62:289–321. Geuens T, Bouhy D, …
