Clinical Trials

Niche drugmaker Quantum in takeover talks with rival Clinigen

Shares in drugmaker Quantum Pharma leapt 12pc today after it confirmed it was in takeover talks with larger £1bn-plus valued rival Clinigen.<p>Both firms are listed on London’s junior market Aim and specialise in making niche medicines.<p>County Durham-based Quantum told investors it had received an …

Tandem Diabetes launches clinical trial for its automatic insulin delivery suspension

Touchscreen insulin pump maker Tandem Diabetes announced a new clinical trial for an insulin pump with a predictive low glucose suspend (PLGS) …

OMF - Joan Janssen, 53, ovarian cancer, Sun Prairie, WI, with Stephanie Morrissey, RN, Dana-Farber 8-15-17

Joan Janssen was diagnosed with ovarian cancer in 2010 in Wisconsin. Her cancer responded well to initial therapies. Unfortunately, Joan's cancer …

K&C - Mindy Schutte, 41, gastrointestinal sarcoma (digestive tract cancer), Highbridge, WI, with Dr. Priscilla Merriam, medical oncologist, Dana-Farber 8-15-17

‘Right to Try’ Bill Could Face Slower Action in House

Changes to measure possible during Energy and Commerce markup<p>A Senate-passed bill intended to help dying patients access experimental drugs will …

Why Asthmatics Should Ignore This New Clinical Trial

Methylprednisolone is a prescription drug used to treat conditions involving inflammation, like asthma, arthritis, gout, tendinitis, transplant …

US biotech Spark hires UK team as cure for inherited blindness edges closer

US biotech Spark Therapeutics has set up a UK office as it targets a rapid launch of its under-review gene therapy for a form of inherited blindness.<p>The Nasdaq-listed firm, which has a market cap of $2.4bn (£1.8bn), is at the forefront of the emerging global field of gene therapies for serious and …

Achieve Life Sciences cleared to start U.S. clinical trials on smoking cessation med cytisine; shares ahead 18% premarket

Thinly traded nano cap Achieve Life Sciences (NASDAQ:ACHV) perks up 18% premarket on light volume in response to its announcement that the FDA has …

U.K. Health Service Turns to Clinical Trial to Make Cheaper HIV Drug Available

The NHS will use a generic version of Truvada, made by Mylan, without infringing Gilead’s patent<p>A branded HIV drug that has been shown to reduce the risk of infection with the virus by 86% is proving too expensive for some at-risk European patients.<p>England’s National Health Service thinks it has a …

England's NHS Turns to Clinical Trial to Make Cheaper HIV Drug Available -- 2nd Update

A branded HIV drug that has been shown to reduce the risk of infection with the virus by 86% is proving too expensive for some at-risk European patients.<p>England's National Health Service thinks it has a solution.<p>The high price of Gilead Sciences Inc.'s HIV drug Truvada has deterred many countries …

Premarket Losers as of 9:05 am

• ETRM -40% on announcing proposed underwritten public offering.<br>• JCP -23% on Q2 earnings.<br>• SNAP -11% on Q2 earnings miss.<br>• NVDA -5% on Q2 earnings.<br>• Now read: …

Call to halt heart trial raises vexing questions

Charging that thousands of patients are being misled and may be unnecessarily placed at increased risk of death, a U.S. watchdog group last week …

Immunotherapy succeeds in thwarting Type-1 diabetes in study

A form of immunotherapy gaining ground as a way to treat childhood food allergies has shown promise in treating another rising scourge of children and young adults: Type 1 diabetes.<p>In a small but rigorous clinical trial, British investigators gave patients recently diagnosed with the metabolic …

Individualized Skin Cancer Vaccines Have Success In Two Clinical Trials

A new method for treating melanoma skin cancer has shown promise in two clinical trials. Unlike uniform removal or drug treatment of cancerous cells …

CARsgen Launches First-in-Class Anti-Claudin18.2 CAR-T Clinical Trial

SHANGHAI, Aug. 10, 2017 /PRNewswire/ -- CARsgen Therapeutics (CARsgen), a global leader in developing chimeric antigen receptor T-cell (CAR-T cell) therapies for solid tumors, today announced its first-in-class anti-Claudin18.2-CAR-T cell therapy for gastric and pancreatic cancers has entered into …

Who Will Use Open Data?

Who is open science for, and why should you care?

Devastated: Why Resapp Health Ltd shares just plunged 80%

The <b>Resapp Health Ltd</b> (ASX: RAP) share price fell 81% to $0.06 this morning, after the company’s announcement of its Smartcough C study results. The …

14 Best Side Jobs For Fast Cash

When you need money fast, you have several options. You could sell a bunch of stuff, refinance the house, or borrow money from friends or relatives. …

Women have heart attacks too, but their symptoms are often dismissed as something else

<i>Men and women respond differently to diseases and treatments for biological, social and psychological reasons. In this series on Gender Medicine,</i> …

DelMar Pharmaceuticals: Where We Are Headed

DelMar Pharmaceuticals is a biopharmaceutical company devoted to the development of unique cancer therapies to address unmet medical needs.<p>The …

The rare cancer that left Lauren no other option but amputation

The first Lauren Poole had heard of epithelioid sarcoma was the day she was told her thumb had to be amputated to save her life.<p>The tiny lump on the …

How women stopped being treated as 'small men' in medicine

Until the turn of this century, there was little sense in Western medicine that gender mattered. Outside the niche of female reproductive medicine, …

MyoKardia shares surge 32% on positive mid-stage trial results for heart muscle disease

MyoKardia Inc. MYOK, +3.54% shares surged 31.8% in premarket trade Monday on positive mid-stage clinical trial results for its mavacamten therapy. Patients on the therapy met the trial's primary endpoint and key secondary endpoints in the phase 2 trial, the company said. MyoKardia expects to start …

A clinical trial saved my life. It could save yours, too.

It was the best decision I ever made, yet many doctors don't recommend trials and most cancer patients aren't inclined to participate.<p>Arizona Senator John McCain’s battle with a rare brain cancer has people thinking the worst. I know from very personal experience that the worst isn’t always what’s …

The Week’s Awesome Stories From Around the Web (Through August 5)

<b>TRANSPORTATION</b><b>A Pod Races Through the Hyperloop for the First Time Ever</b><br>Alex Davies | WIRED<br>“Once loaded into a 1,600-foot-long concrete tube in the …

Clinical Trial Suggests Parkinson’s Can Be Halted

It may be possible to stop the progression of Parkinson’s disease with exenatide, a drug typically used to treat Type 2 diabetes, a new U.K. clinical trial suggests. Parkinson’s gradually damages the brain as cells that produce dopamine start dying. Currently, drugs can help manage the symptoms, …

'I Swallowed a Balloon For Weight Loss and Lost 40 Lbs.'

<i>Dana Goossens, 29, lives in Illinois and participated in a recent clinical trial for a weight loss device called the Obalon Balloon System. Here's</i> …

Waiving clinical trials for proven drugs can benefit India if done with precautions

The Indian government has recently proposed a waiver on clinical trials for proven drugs, if the drug has been approved and marketed (with no major …

Scientists successfully used CRISPR to fix a mutation that causes disease. This is huge.

CRISPR/Cas9 is a gene editing technology that’s revolutionizing science at a breathtaking pace.<p>One of its most exciting, taboo, and controversial applications is tweaking the genes of eggs, sperm, or early embryos to alter a human life. This could one day mean the ability tocreate smarter or more …

Sky's The Limit For Ziopharm

Ziopharm is moving into a pivotal trial for the Ad-RTS-hIL-12 + Veledimex treatment for Glioblastoma ((GBM)).<p>The progression with the Point-of-Care …