Clinical Trials

Absorption of vaginal estrogen cream during sexual intercourse: a prospective, randomized, controlled trial. - PubMed

OBJECTIVE:<p>To determine if intercourse changed serum estradiol levels in women using vaginal E2 cream or in their male partners.<p>STUDY …

Medicine

Novartis Tests New Alzheimer's Drug on People Who Don't Have the Disease

Novartis AG thinks its best bet for testing two new Alzheimer's drugs is on people who don't actually have Alzheimer's.<p>The Swiss drug giant is looking for people whose genes put them at high risk of developing Alzheimer's, but who haven't yet fallen victim to the mind-robbing disease. It hopes such …

Dementia

Can Placebos Work If You Know They're Placebos?

NPR's Mary Louise Kelly asks writer Robert Siegel about "open label placebos" and whether placebos work even when patients know they're placebos. He wrote about his experience in <i>Smithsonian Magazine</i>.

Medicine

What's the secret behind the benefits of whole-body vibration training in patients with COPD? A randomized, controlled trial. - PubMed

BACKGROUND:<p>Several studies have shown that whole-body vibration training (WBVT) improves exercise capacity in patients with severe COPD. The aim of …

Exercise

Not all probiotic yogurts are created equal. Does yours measure up?

If you eat probiotic yogurt to ease irritable bowel symptoms such as bloating and gas – or to ward off colds and flu – you might want to rethink your reason for doing so.<p>It turns out that many probiotic yogurts sold in grocery stores contain too few good bacteria to offer the health benefits …

Medicine

Scientists Just Discovered an Unexpected 'Side Effect' of Aspirin

For years, scientists have been eyeing baby aspirin as a possible aid in preventing cancer — like an "apple a day"-type situation but, instead of an …

Medicine

Cytokinetics: Stretching For The Winner's Circle

There are major needs for new and more effective treatment options related to malfunctions with our human muscular system.<p>Major drug companies are in …

Medicine

Ibrutinib Better Than Bendamustine for OS in CLL, Indirection Comparison Suggests

Results of a systematic literature search published online in Clinical Lymphoma, Myeloma & Leukemia showed that ibrutinib (Imbruvica) was associated …

Medicine

15 Women Share Why They're Marching for Science

Scientists and science lovers are taking to the streets April 22nd for the first-ever March for Science. The march is poised to be one of the largest …

Lifestyle

Cancer Vaccines: Immunotherapy’s New Wave | SCRI - Singapore Clinical Research Institute

<i>Source: Global Health and Travel. Permission required for reproduction.</i><p>Last August, doctors at the National Cancer Centre Singapore (NCCS) announced …

Cancer

Upfront Immunotherapy for Metastatic Kidney Cancer

<b>Transcript:</b><p><b>Robert A. Figlin, MD:</b> So, I think, David, that summary by Toni puts us on alert for what may be a paradigm shift in what’s available in …

Cancer

Gilead's Harvoni produces 100% cure rate in adults co-infected with HCV and HBV in mid-stage study, 99% in children

Results from two Phase 2 clinical trials assessing Gilead Sciences' (GILD -0.9%) Harvoni (ledipasvir/sofosbuvir) in special patient populations …

HIV

BeiGene Announces Initiation of First Pivotal Study in China of PD-1 Antibody BGB-A317

BEIJING, April 21, 2017 (GLOBE NEWSWIRE) -- BeiGene, Ltd. (BGNE), a clinical-stage biopharmaceutical company developing molecularly targeted and …

Medicine

Patients With Fibromyalgia Syndrome Might Have Increased Risk of Peptic Ulcer Disease

April 21, 2017<p>Older patients with fibromyalgia syndrome were especially vulnerable.<p>Patients with fibromyalgia syndrome (FMS) are 1.40 times more …

Chronic Pain

Two older drugs could be 'repurposed' to fight dementia

Dementia is a leading cause of chronic disease in older adults<p>"Depression and cancer drugs offer hope for dementia sufferers," Sky News reports. The …

Dementia

Why Rigel Pharmaceuticals Investors Should Come Back Later

RIGL has now submitted an NDA for fostamatinib in the chronic ITP indication.<p>While the company and investors await word on the NDA there is little to …

Medicine

Text Mining to Improve the Health of Millions of Citizens

<i>By Kenji Takeda</i>, Director of Azure for Research at Microsoft.<p>Doctors face daily decisions about the best care for their patients, and their own …

Machine Learning

Protalix BioTherapeutics Is Positioned Well For The Future

Investigational cystic fibrosis therapy alidornase alfa demonstrated positive results in phase 2 clinical trials, better than current …

Investing

Gilead's Vemlidy shows positive benefit in two long-term HBV studies

Long-term results (96 weeks) from two Phase 3 studies assessing the safety and efficacy of Gilead Sciences' (NASDAQ:GILD) Vemlidy (tenofovir …

HIV

Medidata To Acquire Mytrus For Patient eConsent System

Research software firm Medidata will acquire Mytrus for an undisclosed sum.<p>Mytrus has created a patient clinical trial eConsent system that makes it …

Informatics

Google wants 👅, 😢, and 💩 samples from 10,000 people for a massive medical study

Google and its sister company, Verily, are taking a classic medical research study design and giving it a Silicon Valley spin.<p>The companies, along with researchers from Duke and Stanford universities, will monitor the health of 10,000 people for four years each, using a battery of gadgets and …

Google

Responding to SBM Critics

I started this blog not only to create a useful resource but to have a conversation. As our tagline suggests, we want to explore (not dictate) the …

Research

Records Found in Dusty Basement Undermine Decades of Dietary Advice

If biology has an Indiana Jones, it is Christopher Ramsden: he specializes in excavating lost studies, particularly those with the potential to …

Nutrition

Oats appear safe for patients with celiac disease

Adding oats to increase the nutritional value of a gluten-free diet does not appear to affect symptoms, histology, immunity or serologic features of …

Gluten

Donald Trump Is Threatening My Only Chance At a Healthy Future

Just because I'm sick doesn't mean I don't exist.<p><i>In this op-ed,</i> Teen Vogue <i>editor Kaleigh Fasanella explores how Donald Trump's proposed budget cuts to medical research would impact her personally as someone living with a rare genetic skin condition, in addition to the detrimental affects it would</i> …

Medicine

The Most Effective All-Natural Remedy for Hot Flushes

Those pesky hot flushes can strike at any time.<p>If you see a female friend or colleague sitting in front of a desk fan in winter while everyone else …

Health Information

Too many studies have hidden conflicts of interest. A new tool makes it easier to see them.

PubMed, the Google of scientific search, is now publishing funding information in its abstracts.<p>I once got a press release about a "landmark” study showing cranberry juice could cut the risk of urinary tract infections.<p>This study piqued my interest. All the credible research I’d seen on cranberry …

Research

Here's Why the Best Is Yet to Come for Exelixis, Inc.

<b>Exelixis</b> (NASDAQ: EXEL) has been on a tear over the last year, nearly quadrupling.<p>EXEL data by YCharts.<p>While much of the growth in Exelixis' stock price has to do with the better-than-expected launch of Cabometyx in kidney cancer, the biotech still has room to run.<p>Motley Fool Founders Issue New …

Investing

Health system in Wisconsin tapped for cancer trial

Health care facilities in La Crosse and Onalaska are looking to recruit 6,000 women for a nationwide clinical trial being done to gauge whether blood …

Cancer

Prima BioMed Receives Approval for Third Cohort of Phase I Melanoma Trial

SYDNEY, Australia, April 18, 2017 (GLOBE NEWSWIRE) -- Prima BioMed Ltd (ASX:PRR) (PBMD) (“Prima” or the “Company”) today announced that approval has …

Oncology