Bioinformatics

Artificial intelligence: Activating humanity's god mode

Broadcast:Sunday 22 July 2018 6:05AM<p>The heyday of <i>World of Warcraft</i> saw online players interacting together and forming guilds. Today, artificial …

Artificial Intelligence

Novel bioinformatics approach identifies transcriptional profiles of lineage-specific transposable elements at distinct loci in the human dorsolateral prefrontal cortex | Molecular Biology and Evolution

Expression of transposable elements (TE) is transiently activated during human preimplantation embryogenesis in a developmental stage- and cell …

Neuroscience

New training platform for big data analysis

Studies indicate that more than 95 percent of researchers in the life sciences are already working with big data or plan to do so—but more than 65 …

Tutorials

A Look at the DNA Tech Company Helping to Solve Cold Cases

When a life is brutally taken, the only semblance of solace afforded to devastated loved ones and haunted investigators is the possibility of …

Human Interest

New Origami Robot Can Collect Sensitive Sea Creatures Without Harming Them

Possibly the most wholesome invention on planet Earth right now.<p>Deep in the pelagic midwaters of the ocean swim fragile, ethereal sea creatures. Many …

Science

Random Walk with Restart on Multiplex and Heterogeneous Biological Networks | Bioinformatics

Motivation<p>Recentyears have witnessed anexponentialgrowthin thenumberof identified interactions between biological molecules. These interactions are …

Oxford University Press

Accused Child-Killer Charged With Murder and Molestation in Cold Case

Indiana authorities formally charged John D. Miller, the man who allegedly raped and killed an 8-year-old girl in 1988, with child molestation and …

Crime

Dynamic compression schemes for graph coloring | Bioinformatics

Motivation<p>Technological advancements in high-throughput DNA sequencing have led to an exponential growth of sequencing data being produced and stored …

Oxford University Press

Cryfa: a secure encryption tool for genomic data | Bioinformatics

Summary<p>The ever-increasing growth of high-throughput sequencing technologies has led to a great acceleration of medical and biological research and …

Oxford University Press

China is Using Mass Pee and Poo Surveillance to Police Illegal Drug Use

Police in dozens of Chinese cities are sifting through human waste to track narcotics rings and drug programs.<p>The pee and poo of Chinese citizens have become veritable gold to police surveilling local drug use. Dozens of cities in China are now forensically analyzing sewage for drug consumption, …

Biotechnology

Reproducible and replicable comparisons using SummarizedBenchmark | Bioinformatics

Summary<p>Benchmark studies are widely used to compare and evaluate tools developed for answering various biological questions. Despite the popularity …

Data Science

MAVIS: Merging, Annotation, Validation, and Illustration of Structural variants | Bioinformatics

Summary<p>Reliably identifying genomic rearrangements and interpreting their impact is a key step in understanding their role in human cancers and …

Oxford University Press

The depths of the ocean and gut flora unravel the mystery of microbial genes

Surprisingly, the functions of a huge number of microbial genes are still unknown. This knowledge gap can be thought of as ''genomic dark matter'' in …

Biology

Simulating Illumina Metagenomic Data with InSilicoSeq | Bioinformatics

Motivation<p>The accurate in-silico simulation of metagenomic datasets is of great importance for benchmarking bioinformatics tools as well as for …

Command-line

Kinome-wide identification of phosphorylation networks in Eukaryotic proteomes | Bioinformatics

Motivation<p>Signaling and metabolic pathways are finely regulated by a network of protein phosphorylation events. Unraveling the nature of this …

Neuroscience

Pristine Antarctic fjords contain similar levels of microplastics to open oceans near big civilisations

In the middle of the last century, mass-produced, disposable plastic waste started washing up on shorelines, and to be found in the middle of the …

Global Warming

What Does This Deep-Sea Expedition Mean For The Indigenous Haida Nation?

The archipelago of Haida Gwaii sits 62 miles off the coast of British Columbia, Canada, where members of the Haida nation have lived for millennia and currently make up half of the islands’ 5000-person population. The Haida Nation’s territory consists of the islands of Haida Gwaii, land in …

Molecular Biology

Think You've Got Nothing to Hide? Think Again — Why Data Privacy Affects Us All

We all hear about privacy, but do we really understand what this means? According to privacy law expert Robert B. Standler, privacy is “the …

Privacy

Natural product that could lead to new class of commercial herbicide: Bioinformatics approach used to uncover the weed killer could also be used to find new drugs for medications

Bioinformatics approach used to uncover the weed killer could also be used to find new drugs for medications<p>A team of engineers and scientists …

Biotechnology

Matt : Unix tools for alternative splicing analysis | Bioinformatics

Summary<p>Tracking thousands of alternative splicing (AS) events genome-wide makes their downstream analysis computationally challenging and laborious. …

Oxford University Press

parallel computational framework for ultra-large-scale sequence clustering analysis | Bioinformatics

Motivation<p>The rapid development of sequencing technology has led to an explosive accumulation of genomic data. Clustering is often the first step to …

Machine Learning

SPUTNIK: an R package for filtering of spatially related peaks in mass spectrometry imaging data | Bioinformatics

Summary<p><i>SPUTNIK</i> is an R package consisting of a series of tools to filter mass spectrometry imaging peaks characterized by a noisy or unlikely spatial …

Imaging

Broom: Application for non-redundant storage of High Throughput Sequencing data | Bioinformatics

Motivation<p>The data generation capabilities of High Throughput Sequencing (HTS) instruments have exponentially increased over the last few years, …

Genetics

Comparative assessment of different familial aggregation methods in the context of large and unstructured pedigrees | Bioinformatics

Motivation<p>Familial aggregation analysis is an important early step for characterizing the genetic determinants of phenotypes in epidemiological …

Oxford University Press

Local Graph Clustering

Local Graph Clustering provides<p>methods that find local clusters in a given graph without touching the whole graph<br>• methods that improve a given …

Data Science

If you give your DNA and tissues to science, should you get a peek at what they might contain?

As the tissue samples and DNA of more and more people are shared with researchers, the question of what information buried in those samples to give …

Molecular Biology

Metagenomic binning through low-density hashing | Bioinformatics

Motivation<p>Vastly greater quantities of microbial genome data are being generated where environmental samples mix together the DNA from many different …

Molecular Biology

What happens when you take a bunch of medications? A new algorithm could help doctors figure it out - Scope

People take a lot of drugs: According to the CDC, about a quarter of us took two prescription drugs in the last month, and people over 65 routinely …

Medicine

Renewing Philosophy of Religion: Exploratory Essays // Notre Dame Philosophical Reviews // University of Notre Dame

"A traveller of good judgment may mistake his way, and be unawares led into a wrong track . . . but when it ends in a coal-pit, it requires no great …

Philosophy

Accurate multiple alignment of distantly related genome sequences using Filtered Spaced Word Matches as anchor points | Bioinformatics

Motivation<p>Most methods for pairwise and multiple genome alignment use fast local homology search tools to identify <i>anchor points</i>, i.e. high-scoring …

Genetics