Thasso Post Magazine

By Thasso | Thasso created a magazine on Flipboard. “Thasso Post Magazine on Flipboard” is available with thousands of other magazines and all the news you care about. Download Flipboard for free and search for “Thasso”.

DNMT3B gene variant influences nicotine dependence

December 09, 2017 – Newest research has revealed that a DNMT3B gene variant influences nicotine dependence identified in people of European …

Research

Gene expression and ethnicity: Does it matter?

<b>December 05, 2017 –</b> We are entering the age of precision medicine, in which diagnosis and therapy decisions for each patient will be based on …

Matched

Placebomics: Where placebo and genetics meet

<b>December 01, 2017 –</b> The placebome is a new game in town. That is where genetics and the placebo effect meet. The underlying discipline of study may …

Neuroscience

The nightmare: Sudden cardiac arrest in competitive sports

<b>November 23, 2017 –</b> We all have heard of it: While in full action of the game, a young soccer player collapsed on the field and died. Same for a …

Medicine

Cancer is not like cancer: Ethnic background matters

A new study just published in PLOS Genetics shows that multiple myeloma patients of European descent were six times more likely than their …

Cancer

Are there life-threatening health problems with Limbrel?

Currently, the FDA is investigating serious adverse events involving Limbrel (Flavocoxid). While a range of adverse events have been reported, two …

Medicine

Obeticholic Acid (Ocaliva): Is there a serious drug safety problem?

<b>September 30, 2017 –</b> Obeticholic acid (Ocaliva) was approved by the American Food & Drug Administration (FDA) in May 2016 for the treatment of …

Medicine

Amish People: Old age because of genetic mutations?

However, the researchers quicly realised that those individuals with a mutation on only one of these copies (i.e., being heterozygous for that …

Longevity

Febuxostat (Uloric): Gout medication with increased risk for heart-related death?

Ph.D.; Professor in Pharmacology and Toxicology.<br>Senior expert in theragenomic and personalized medicine and individualized drug safety.<br>Senior expert …

Medicine

Abilify MyCite, the first digital pill. Where does all that silicone go?

Ph.D.; Professor in Pharmacology and Toxicology.<br>Senior expert in theragenomic and personalized medicine and individualized drug safety.<br>Senior expert …

Health

Treatment for the rare genetic disorder MPS VII approved

MPS VII is a lysosomal storage disorder caused by deficiency of an enzyme called beta-glucuronidase, which causes an abnormal buildup of toxic …

Medicine

Spinal Muscular Atrophy: Single-Dose Gene-Replacement Therapy

<b>November 12, 2017 –</b> Spinal muscular atrophy type 1 (SMA1) is a progressive, monogenic motor neuron disease with an onset during infancy that results …

Personomics: The Missing Link from Precision Medicine to Personalized Medicine

<b>October 21, 2017 –</b> Just seen on PubMed:<p>Ziegelstein RC J Pers Med 2017 Oct;7(4)<p>PMID: 29035320<p>Abstract<p>It is all about people who one day may turn into …

Childhood brain tumors: Genetic variability amenable to individualized therapy approaches

<b>October 02, 2017 –</b> Seemingly incurable childhood brain tumor is one of the most devastating clinical diagnosis a young patient and her/his family can …

Chagas disease: First time approval of a treatment in the US

<b>August 31, 2017 –</b> For the very first time, the American Food & Drug Administration (FDA) granted approval for a treatment of Chagas disease in the …

Medicine

Genetic Biomarker Tied to Suicide Risk in Schizophrenia

On the molecular level, the SNP rs300774 also contributed to the expression of genes related to cholesterol biosynthesis, and subsequent analyses …

Lifeomics: Epigenetic DNA methylation-based life insurance?

<b>Mai 07, 2017 –</b> Genetics- and/or genomics-based approaches are penetrating every single aspect of human life. In contrast to the term <b>theragenomics</b> …

Bisphosphonates: GGPS1 Mutation and Atypical Femoral Fractures

<b>May 05, 2017 –</b> This report nicely illustrates how, by both clever study design and selection of according phenotypic patients, genetic …

Risk of severe if not fatal skin reactions with Pembrolizumab (Keytruda)

Healthcare professionals including oncologists, nurses, hospital pharmacists, emergency room staff, and cancer clinic staff should <b>i)</b> counsel patients …

CDH2 gene to cause sudden death in young people

“This is important news for families who have had a young family member suffer a sudden cardiac death, for them to know a genetic cause has been …

Brodalumab (Siliq) with a fatal touch: New psoriasis drug approved

<b>February 16, 2017 –</b> The American Food & Drug Administration (FDA) just approved Brodalumab (Siliq) to treat adults with moderate-to-severe plaque …

Medicine

Genetic predisposition and sweating: Most Koreans don't have to wear deodorants

<b>February 08, 2017 –</b> Genetic predisposition may go in both ways, the positive and the negative. Usually, when we talk about genetic predisposition, …

Massaging of data and outcomes: Can we ever trust clinical trial outcomes reported by Pharma?

Paroxetine is prescribed for depression, anxiety, panic attacks, post-traumatic stress disorder (PSTD), obsessive compulsive disorder (OCD), and most …

Orlistat: Assessment of Adverse Events in Protocols, Clinical Study Reports, and Published Papers

Orlistat (Xenical)<p><b>August 30, 2016 –</b> The present article which just appeared in August 2016 issue of PLOS Medicine illustrates how the inaccurate and …

Eltrombopag (Revolade) can cause severe hepatotoxicity and potentially fatal liver injury

<b>August 26, 2016 –</b> Eltrombopag is a medication that has been developed for certain conditions that lead to thrombocytopenia (abnormally low platelet …

Medicine

Precision Medicine Initiative: draft guidances issued

Powerful new technologies, known as next generation sequencing (NGS), can scan a person’s DNA to detect genomic variations that may determine <b>i)</b> …

Aspirin: Does OTC mean without serious health risks?

In 2009, a warning about the risk of serious bleeding was added to the labels of all OTC products that contain NSAIDs, including aspirin-containing …

Are first-in-man (FIM) clinical trials unsafe?

Thus, EMA has started a review of the guidelines currently applicable that describe first-in-man (FIM) clinical trials and the data needed to enable …

We knew it all along: It's all in the genes, and success in dating is no exception

Human Nature<p>The research team wanted to find out if mate selection could actually be influenced by people’s ability to quickly detect socially …

Relationships