Taylor Weymouth Hanton
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What is the most common cyanotic lesion presenting in the newborn period? transposition of the great arteries is the most common form of cyanotic congenital heart disease in neonates and accounts for 6-10% of infants with congenital heart disease. In children "outside" the newborn period, tetralogy of Fallot is the most common, representing 7-9% of cardiac cases of cyanosis.
Do breast-fed infants require iron supplementation? Although the bioavailability of iron in breast milk is high (because of the presence of lactoferrin, which enhances iron absorption), the content is relatively low. Additional sources of iron are recommended for breast-fed infants after 4-6 months of age.
significance of facial port-wine stains in neoborn: Port-wine stains can occur as isolated cutaneous birthmarks in association with structural abnormalities of choroidal vessels of the eye leading to glaucoma, and of the leptomeningeal vessels in the brain leading to seizures (Sturge-Weber syndrome). Almost invariably, the hemangioma involves the homolateral trigeminal V1 area or is bilaterally distributed. Ophthalmologic assessment and radiologic studies (computed tomography [CT] or MRI) are indicated for children who exhibit hemangiomas in the upper eyelid or forehead.
When bilirubin reaches the liver, it is transported into a liver cell and binds to ligandin. The concentration of ligandin is low at birth and increases rapidly over the first few weeks of life. It is then bound to glucuronic acid in the endoplasmic reticulum by the uridine diphosphoglucuronyltransferase (UDPGT) enzyme. This conjugated molecule is water soluble and can be excreted into bile. The production of UDPGT is low at birth and rises steadily over the first 4-8 weeks of life. Once excreted into the bile, the molecule is further degraded by microbes in the colon and excreted; however, some deconjugation does occur in the small intestine, and this unconjugated molecule can be reabsorbed into the enterohepatic circulation, increasing the total plasma bilirubin. This is an important factor in neonatal jaundice due to the limited nutrient intake in the first few days of life, which prolongs intestinal transit time and allows for increased reabsorption
Bilirubin is the end product of red blood cell breakdown and occurs through a series of oxidative reactions. Approximately 75% is derived from hemoglobin. Bilirubin is relatively water insoluble and is transported in the plasma tightly bound to albumin. Binding increases postnatally with age and is reduced in sick infants. A small fraction of unconjugated bilirubin circulates unbound, and this free portion is able to cross lipid-containing membranes, including the blood-brain barrier, leading to neurotoxicity. In the fetus, bilirubin freely crosses the placenta and is excreted by the mother. Image courtesy of Jayashree Ramasethu, MD, Georgetown University Medical Center.
<b>By Haley Pierson-Cox</b><p>For me, summer in NYC means two things: 1) I will eventually wear a light skirt into the subway when my hands are full, and 2) on that day, when I step onto the stairs of the station, a gust of wind will come barreling up from below, lifting my skirt and showing my backside to …Sewing
Want to make a perfectly sharp corner without breaking out the fabric scissors? Check out this sharp corner sewing tutorial from Tilly and the Buttons!Sewing
By onJanuary 16, 2013 in Inspiration and Everything Else<p>Hey, everyone! Finally, I’ve picked up the pieces of my Striped Renfrew Top and started to …
Check out these instructions for making things that hold other things. Maybe you know somebody who needs a handmade gift?<p>iPad or Kindle cover …
Welcome to the new home of LoveSewing and The Sewing Studio!<p>When I first started teaching sewing classes in my Toronto apartment at night while I …