Stephanie Wyborski

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Proposed Treatment To Fix Genetic Diseases Raises Ethical Issues

The federal government is considering whether to allow scientists to take a controversial step: make changes in some of the genetic material in a woman's egg that would be passed down through generations.<p>Mark Sauer of the Columbia University Medical Center, a member of one of two teams of U.S. …

Down's syndrome cells 'fixed' in first step towards chromosome therapy

Scientists have corrected the genetic fault that causes Down's syndrome – albeit in isolated cells – raising the prospect of a radical therapy for the disorder.<p>In an elegant series of experiments, US researchers took cells from people with DS and silenced the extra chromosome that causes the …

Shutting Down the Extra Chromosome in Down’s Syndrome Cells

Many genetic disorders are caused by faulty versions of a single gene. In the last decade, scientists have made tremendous strides in correcting these faults through “gene therapy”—using viruses to sneak in working versions of the affected genes.<p>But some disorders pose greater challenges. Down’s …

Drug Cures Mice Of Down Syndrome With A Single Dose

But it's not a cure for humans yet.<p>Cure Down syndrome with a single injection? Well, maybe--if you're a mouse. A team of scientists from John Hopkins University and the National Institutes of Health have cured newborn mice of Down syndrome by injecting them with a drug that stimulates what's called …