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Chemotherapy at end of life can cause more suffering

Treating terminally ill cancer patients with chemotherapy in the months or weeks before death doesn’t improve quality of life and may actually do …

Cancer

Tough brain tumors may have a weak spot

Some brain tumors are notoriously difficult to treat. Whether surgically removed, zapped by radiation, or infiltrated by chemotherapy drugs, they …

Cancer

Berry extract added to chemo kills pancreatic cancer

A chemotherapy drug was more effective at killing pancreatic cancer cells when an extract from chokeberries was added to the mix.<p>Chokeberry is a wild …

Cancer

Bacterial ‘chatter’ tells cancer cells to die

Scientists can manipulate a molecule used as a communication system by bacteria to prevent cancer from spreading. This communication system can tell …

Cancer

Coated cells act like camo for deadly brain tumors

Brain tumors are able to go undetected by the immune system if their cells are coated with extra amounts of a specific protein.<p>The discovery, made in …

Immune System

2 drugs work better than 1 to stop cancer

A new combination drug dramatically slows tumor growth in mice with few side effects.<p>Researchers combined two drugs: a COX-2 inhibitor, similar to …

University of California

Cancer relies on three-way switch to decide to spread

When cancer cells decide to metastasize and invade other parts of the body, they rely on a genetic on-off switch. Now physicists say they’ve decoded …

Cancer Cells

Pulses of light turn on cancer ‘death signal’

Researchers have created a peptide—a small piece of protein—that when linked to a light-responsive dye is able to switch on death pathways in cancer …

Cardiff University

Combine Chinese herbs with chemo to treat cancer

Combining traditional forms of Chinese and Western medicine could lead to new treatments for liver, lung, colorectal cancers, and osteosarcoma of the …

Cancer

Drug erases brain tumor in mice

A re-purposed, FDA-approved drug can stop and ultimately erase human brain tumor cells implanted in mice.<p>Encouraged by the findings, researchers now …

Cancer

Compound clears cancer drug’s ‘mental fog’

An existing drug compound appears to eliminate the nasty side effect of a breast cancer drug that causes a mental fog similar to “chemo …

Cancer

‘Out of control’ mucus shields cancers from treatment

A controversial drug may offer a way to reduce the mucus shield that coats cancer cells and allows them to multiply and spread.<p>Researchers found that …

Cancer Cells

Molecule quiets cancer cell ‘chatter’

A new compound interrupts the “conversation” between cancer cells to put the brakes on tumor growth.<p>While great strides have been achieved in cancer …

In Vivo

Tiny capsules deliver brain cancer drugs by ‘electrojet’

Drugs delivered in consistently uniform microcapsules may offer an easier, more tightly controlled way to treat brain cancer.<p>“Brain tumors are one of …

Penn State

Tool ‘sees’ invisible tumors in brain tissue

A new laser-based tool could dramatically improve the accuracy of brain tumor surgery, researchers say.<p>The technology would allow surgeons to tell …

University of Michigan

Scientists pinpoint ‘root cause’ of 30 common cancers

<b>U. QUEENSLAND (AUS) —</b> Scientists have identified signature mutations that drive tumor growth in 30 of the most common cancer types.<p>The team analyzed …

Cancer

After radiation, sleeping brain cells wake up

<b>JOHNS HOPKINS (US) —</b> Stem cells in the brain resist cancer-killing radiation treatments and can be reactivated to replace injured cells—and …

Neuroscience

Medicine gets personal to stop brain tumor ‘drivers’

<b>COLUMBIA U. (US) —</b> Researchers have identified 18 new genes that drive the most common—and most aggressive—form of brain cancer in adults.<p>“Once you …

Mutations

Therapy filters cancer that chemo misses

<b>PENN STATE (US) —</b>Many cancers, including breast and prostate cancers, can spread to the brain, but researchers say filtering malignant cells out of …

Cancer

Drug works better if cancer can’t sleep

<b>U. PITTSBURGH (US) —</b> Keeping cancer cells from entering a state of cellular sleep makes cancer drugs more effective and lowers the chance of cancer …

Cancer

This chemical keeps naked mole rats cancer-free

<b>U. ROCHESTER (US) —</b> Naked mole rats don’t appear to get cancer and biologists have identified the chemical that may explain why.<p>The rodents are …

Biology

Inhaled chemo kills more lung tumors

<b>RUTGERS (US) —</b> Delivering chemotherapy through inhalation significantly improves the rate of successfully treating cancer tumors in the lungs, new …

Cancer

‘Master switch’ may be key to brain cancer

<b>U. VIRGINIA (US) —</b> A new target shows promise for treating deadly glioblastomas while avoiding many of the obstacles of previous …

Cancer

Polio virus engineered to kill brain tumor

<b>DUKE (US) —</b> A modified polio virus appears to be effective in attacking glioblastoma brain tumor cells, researchers report in an early study to …

Immunotherapy

Block one gene to make cancer less aggressive

<b>JOHNS HOPKINS (US) —</b> Repressing a critical control gene can stop runaway cancer cell growth and the processes that spread tumors around the body, …

Cancer

How ‘jail-breaker’ cancer cells escape

<b>PRINCETON (US) —</b> Cancer cells that can break out of a tumor and invade other organs are more aggressive than nonmalignant cells and are nimble enough …

Cancer

Grow stem cells in lab with one simple step

<b>U. PITTSBURGH (US) —</b> By blocking a single protein, it’s possible to grow large batches of stems cells from mature mammalian cells, researchers …

Stem Cells

‘Pool ball’ cancer therapy cuts side effects

<b>U. MISSOURI (US) —</b> A new form of radiation therapy put cancer into remission in mice without the usual side effects of chemotherapy and radiation, …

Cancer

‘Smart’ chemo drug goes easy on fertility

<b>NORTHWESTERN (US) —</b> A new chemotherapy drug in the form of nanoparticles is less toxic to young women’s fertility but extra tough on cancer, say …

Cancer

Google math predicts lung cancer’s path

<b>USC (US) —</b> A mathematical model like the one Google Search uses to rank webpages also offers insight into how lung cancer spreads.<p>The researchers …

Cancer