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Innate Immune Sensing of Flaviviruses

1. Rust RS (2012) Human arboviral encephalitis. Semin Pediatr Neurol 19: 130–151.<p>2. Petersen LR, Carson PJ, Biggerstaff BJ, Custer B, Borchardt SM, …

Viral Encephalomyelitis

1. Griffin DE (2010) Emergence and re-emergence of viral diseases of the central nervous system. Prog Neurobiol 91: 95–101.DE Griffin2010Emergence …

Feeding Uninvited Guests: mTOR and AMPK Set the Table for Intracellular Pathogens

1. Hood MI, Skaar EP (2012) Nutritional immunity: transition metals at the pathogen-host interface. Nat Rev Microbiol 10: 525–537.<p>2. Terry LJ, Vastag …

Neuroscience

Virus and Host Determinants of West Nile Virus Pathogenesis

1. Brault AC, Huang CY, Langevin SA, Kinney RM, Bowen RA, et al. (2007) A single positively selected West Nile viral mutation confers increased …

How to Make It in the Urinary Tract: A Tutorial by Escherichia coli

1. Foxman B (2003) Epidemiology of urinary tract infections: incidence, morbidity, and economic costs. Dis Mon 49: 53–70.<p>2. Ronald A (2002) The …

Microbiology

Host Susceptibility Factors to Bacterial Infections in Type 2 Diabetes

1. Dooley KE, Chaisson RE (2009) Tuberculosis and diabetes mellitus: convergence of two epidemics. Lancet Infect Dis 9: 737–746.<p>2. Bader MS (2008) …

Igniting the Fire: Staphylococcus aureus Virulence Factors in the Pathogenesis of Sepsis

1. Lowy FD (1998) <i>Staphylococcus aureus</i> infections. N Engl J Med 339: 520–532.<p>2. Angus DC, Linde-Zwirble WT, Lidicker J, Clermont G, Carcillo J, et …

Medicine

Candida albicans Interactions with Bacteria in the Context of Human Health and Disease

1. Shirtliff ME, Peters BM, Jabra-Rizk MA (2009) Cross-kingdom interactions: <i>Candida albicans</i> and bacteria. FEMS Microbiol Lett 299: 1–8.ME …

Microbiology

The Battle for Iron between Bacterial Pathogens and Their Vertebrate Hosts

1. Kehl-Fie TE, Skaar EP (2009) Nutritional immunity beyond iron: a role for manganese and zinc. Curr Opin Chem Biol 14: 218–224.TE Kehl-FieEP …

Biology

The Inflammasomes

1. Lamkanfi M, Festjens N, Declercq W, Vanden Berghe T, Vandenabeele P (2007) Caspases in cell survival, proliferation and differentiation. Cell …

Neuroscience

The 2010 Cholera Outbreak in Haiti: How Science Solved a Controversy

1. United States Geological Survey (2010) Magnitude 7.0 - Haiti region. USGS Earthquake Hazards Program. Reston: United States Geological Survey. …

Environmental Health

Innate Immune Sensing of DNA

1. Takeuchi O, Akira S (2010) Pattern recognition receptors and inflammation. Cell 140: 805–820.O. TakeuchiS. Akira2010Pattern recognition receptors …

Immunotherapy

Evolution of Th2 Immunity: A Rapid Repair Response to Tissue Destructive Pathogens

1. Thomas GR, McCrossan M, Selkirk ME (1997) Cytostatic and cytotoxic effects of activated macrophages and nitric oxide donors on <i>Brugia malayi</i>. …

Immunotherapy

Taste for Blood: Hemoglobin as a Nutrient Source for Pathogens

1. Perutz MF, Rossmann MG, Cullis AF, Muirhead H, Will G, et al. (1960) Structure of haemoglobin: a three-dimensional Fourier synthesis at 5.5-A. …

Microbiology

Inflammatory Responses Associated with the Induction of Cerebral Malaria: Lessons from Experimental Murine Models

1. Schofield L, Grau GE (2005) Immunological processes in malaria pathogenesis. Nat Rev Immunol 5: 722–735.<p>2. Taylor TE, Fu WJ, Carr RA, Whitten RO, …

Neurology

Make It, Take It, or Leave It: Heme Metabolism of Parasites

1. Panek H, O'Brian MR (2002) A whole genome view of prokaryotic haem biosynthesis. Microbiology 148: 2273–2282.<p>2. Roth JR, Lawrence JG, Bobik TA …

Biology

Babesia: An Emerging Infectious Threat in Transfusion Medicine

1. Lantos PM, Krause PJ (2002) Babesiosis: similar to malaria but different. Pediatr Ann 31: 192–197.<p>2. Leiby DA (2011) Transfusion-transmitted …

Medicine

The Cell Biology of Leishmania: How to Teach Using Animations

1. Alvar J, Vélez ID, Bern C, Herrero M, Desjeux P, et al. (2012) Leishmaniasis worldwide and global estimates of its incidence. PLoS One 7: e35671<p>2. …

Biology

Understanding Human Variation in Infectious Disease Susceptibility through Clinical and Cellular GWAS

1. Raychaudhuri S (2011) Mapping rare and common causal alleles for complex human diseases. Cell 147: 57–69.<p>2. Allison AC (1954) Protection afforded …

Genetics

The Role of Mast Cells in the Defence against Pathogens

1. Abraham SN, St John AL (2010) Mast cell-orchestrated immunity to pathogens. Nat Rev Immunol 10: 440–452.SN AbrahamAL St John2010Mast …

Viral

Sleeping with the Enemy: How Intracellular Pathogens Cope with a Macrophage Lifestyle

1. Nandan D, Yi T, Lopez M, Lai C, Reiner NE (2002) <i>Leishmania</i> EF-1alpha activates the Src homology 2 domain containing tyrosine phosphatase SHP-1 …

Tuberculosis