Shams Pather

31 Flips | 4 Magazines | 2 Likes | @shamspather | Keep up with Shams Pather on Flipboard, a place to see the stories, photos, and updates that matter to you. Flipboard creates a personalized magazine full of everything, from world news to life’s great moments. Download Flipboard for free and search for “Shams Pather”

A New Way to Reproduce - MIT Technology Review

Let’s call him B.D., because that’s what his wife does on her infertility blog, Shooting Blanks. Several years ago, the 36-year-old learned he was …

Ancient DNA reveals fate of the mysterious Canaanites

When the pharaohs ruled Egypt and the ancient Greeks built their first cities, a mysterious people called the Canaanites dominated the Near East. …

CRISPR Gene-Editing Could Cause Hundreds of Unexpected Mutations, Study Shows

Uh oh...<p><b>Update (3 April 2018):</b> In late March 2018, the study was officially retracted after the authors could not replicate these results. You can …

Mutations

Q&A: Why HPC is bioinformatics’ best friend

With more than 6.4 billion bases in a single person’s DNA, it’s easy to understand why data analytics is such a huge part of medical science. As data …

Who’s Who in the Fight Against ISIS?

The global fight against ISIS has been halting and complex since it began in late 2014.<p>The United States has led an international coalition of more …

Biogen Drug Shows Early Promise against Alzheimer’s Disease

Preliminary clinical trials with a small group of patients suggest that aducanumab, a drug being developed by Biogen, may be effective in removing …

ISIL is using the language barriers within its ranks to evolve jihad beyond Arabic

<i>ISIL, a.k.a. the Islamic State, has received a lot of attention for its multilingual propaganda and deft use of social media to terrify and recruit. Until now, however, no one has pulled together a detailed portrait of how ISIL is using its polyglot nature to evolve violent jihad beyond Arabic.</i> …

The big thing almost everyone missed about Brexit

To explain why the UK voted to leave the European Union, commentators have zeroed in on four potential reasons: fear of immigrants, voter dissatisfaction with a weak economy or the status quo, loss of national autonomy, and age.<p>The first three explanations are intuitively powerful, but they seem to …

These Are the 5 Best TED Talks Ever, According to the Guy Who Runs TED

The event's boss names the talks that have taught him the most.<p>If you're a massive TED fan like me, you've probably watched a whole lot of the compelling talks by now. But when it comes to consuming all the insights TED has to offer, even the most dedicated enthusiasts can't hold a candle to Chris …

Public Speaking

Shouldn’t We Have A Human Genome Project for Mental Illness?

Success in understanding, treating and preventing specific diseases has often resulted from concentrated research initiatives backed by strong …

Apartheid's Urban Legacy, in Striking Aerial Photographs

An American used drones to capture the color lines still stark in South African cities.<p>Johnny Miller was just starting out as a photographer in Seattle in 2011 when he won a Rotary Ambassadorial Scholarship that took him to Cape Town, South Africa—a country that, like his own, has a long history of …

China’s bid to be a DNA superpower

First China conquered DNA sequencing. Now it wants to dominate precision medicine too.

Genetics

5 terrible illnesses that genetic engineering could eliminate forever

But the potential to use these same technologies to cure intractable diseases is huge.<p>In a 2015 essay for the New England Journal of Medicine, Eric S. Lander, the founding director of the Broad Institute and a professor at Harvard Medical School and MIT, clearly expresses the importance of not …

Genetics

Pioneering cancer drug combination approved

<b>A pioneering pair of cancer drugs that unleash the immune system on tumours will be paid for by the NHS in England.</b><p>In trials, the combination therapy shrank the most aggressive and deadly type of skin cancer in 69% of patients.<p>The decision to approve the drugs is one of the fastest in NHS history …

Scientists eye creating synthetic human genomes in lab

Mapping the genetic code was only complete 13 years ago, but researchers are already setting their sights on another lofty goal – creating a …

Human gene editing research gets green light

WASHINGTON, D.C. — Human gene-editing research, even on embryos, is needed and should go ahead, with one major caveat: No pregnancies can result, …

God's Red Pencil? CRISPR and the Three Myths of Precise Genome Editing

For the benefit of those parts of the world where public acceptance of biotechnology is incomplete, a public relations blitz is at full tilt. It …

Genetics

Mapping more genomes will create a healthcare 'big data revolution'

<i>From helping humans live longer and hacking our performance, to repairing the body and understanding the brain, WIRED Health will hear from the</i> …

Could cures for cancer lie hidden in the cloud?

<b>When Hollywood actress Angelina Jolie found out she carried a faulty variant of the BRCA1 gene, her doctors told her she had an 87% chance of developing breast cancer.</b><p>Armed with this knowledge, she chose to undergo a double mastectomy in 2013 to reduce the risk to around 5%.<p>This kind of genetic …

12 women leading the life sciences movement in Silicon Valley

Breakthroughs in genetic engineering, 3D printing, cloud-based science experiments, A.I. and machine learning technology have created a weird and cool new kind of cutting-edge biotech that goes beyond pharma into what just a few decades ago seemed like magical thinking.<p>And women are leading the …

Researchers enhance CRISPR gene editing technology

Scientists have developed a process that improves the efficiency of CRISPR, an up-and-coming technology used to edit DNA.<p>"Scientists all over the …

CRISPR will change lives, but not only through genetic engineering

By Jacob Corn<p><b>Each week, In Theory takes on a big idea in the news and explores it from a range of perspectives. This week we’re talking about human genetic engineering.</b><p><i>Jacob Corn is scientific director of the Innovative Genomics Institute and a faculty member at the University of California at</i> …

CRISPR Gene Editing Tool Used to Treat Genetic Disease in an Animal For The First Time

It begins here.<p>For the first time, scientists have used CRISPR gene editing to successfully treat a genetic disease inside a fully developed living …

A Landmark Ruling Allows Gene Editing in Human Embryos

It's the first time a national regulatory authority has endorsed gene editing in human embryos.<p>In a landmark ruling, researchers have received approval from British regulators to conduct gene editing ("genetic modification") on human embryos.<p>A group led by biologist Kathy Niakan at London's new …

Designing Medical Devices for the Poorest Four Billion

Let's say you have developed a great prototype, but the prototype needs to get to market. It needs to get to commercialization. Commercialization is key to impact, but we have a real shortage of groups that will support the "unsexy" part of product development - scaling. My plea is - particularly …

The major concern about a powerful new gene-editing technique that most people don't want to talk about

The technique, known as CRISPR/Cas9, lets scientists cut-and-paste DNA inside cells to correct genetic defects or, potentially, add new capabilities. It offers enormous promise to improve our understanding of biology and to treat or even eliminate genetic diseases.<p>But there's a dark side to …

Liking Windows 10 so far? Here's how to make it even better

Windows 10 is great; if you’re on a Windows 7 or 8 PC, there’s virtually no reason not to upgrade.<p>That said, there are so many new features and settings that sorting through them all can become overwhelming, and you could be missing out on making the most of your Windows 10 experience.<p>Don’t worry …

Cancer patient takes BRCA1 gene mutation patent decision to high court

Yvonne D’Arcy is hopeful the high court will overturn a ruling that gives private companies the right to control certain mutations in human genes<p>A long-running fight to stop private companies from owning the rights to isolated human gene mutations has reached Australia’s high court, and is the last …

Here Are The Best Apps For People With Too Much To Do

While some still insist on sticking with pencil and paper to keep track of their daily tasks, many harried professionals are turning to productivity apps to help manage everything from huge projects and deadlines to the little things they need to get done.<p>Productivity apps are in huge demand; …

Apps

Adaptive Biotech Gets $195M To Dig Deep Into The Immune System's Secrets

Adaptive Biotechnologies is helping scientists look at the immune system in a new way, with a combination of DNA sequencing and high-powered computation. Now the small private company just got $195 million from some familiar Wall Street investors to see if its technology platform can really shake …