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HIV flushed out by cancer drug

HIV can be flushed out of its hiding places in the body using a cancer drug, researchers show.

The cornerstone of treatment, anti-retroviral therapy, kills the virus in the bloodstream but leaves "HIV reservoirs" untouched.

The study, published in PLoS Pathogens, showed the drug was "highly potent" …

Cancer

If telomeres are long, lung cancer risk goes up

The protective caps on DNA are called telomeres. Shortened telomeres have been implicated in aging and cardiovascular diseases, but their …

Genetics

Memories of a parasite can linger in the skin

The immune system remembers pathogens it has encountered in the past. T cells with these memories circulate in the blood stream looking for sites of …

Immune System

New Sun-Blocking Material Uses Compounds From Algae And Fish

To block the rays damaging clothes or outdoor furniture

Researchers have used compounds found in algae and reef fish mucus to create a material that naturally blocks harmful UV rays, according to a paper published recently in ACS Applied Materials & Interfaces.

The sunscreen you buy at your local …

Marine Biology

Scientists successfully edit human immune-system T cells

Efficient editing (cutting out) of CXCR4, a protein receptor that HIV can use to infect T cells (credit: Kathrin Schumann et al./PNAS)

In a project …

Medicine

3D brain map reveals connections between cells in nano-scale

Scientists have created an unprecedented high-resolution map of the brain that reveals structures as small as those found in individual nerve cells.

They produced the 3D map from a compilation of images taken with nanoscale resolution, making it possible to pick out features measured in millionths …

The Brain

This cutting-edge research is a huge step in the war against the dangerous mysteries of the brain

A neuron, connected to many others.

If you don't understand a problem, chances are you won't be able to solve it.

That's a major stumbling block for scientists attempting to develop treatments for brain disorders such as autism, depression, dementia, and more that will affect an estimated 100 million …

The Brain

Neanderthals had outsize effect on human biology

From skin disorders to the immune system, sex with archaic species changed Homo sapiens.

Our ancestors were not a picky bunch. Overwhelming genetic …

Life Sciences

Genome-wide mutational spectra analysis reveals significant cancer-specific heterogeneity

Abstract

Cancer is widely recognized as a genetic disease in which somatic mutations are sequentially accumulated to drive tumor progression. Although …

Cancer

Study: The kinds of friendships you have in your 20s and 30s predicts your well-being later in life

A new study shows that when it comes to friendship, it’s quantity over quality that matters in your 20s—and vice versa in your 30s.

That pattern turns out to be a predictor of psychological well-being later in life, and it happens to be one that comes relatively naturally to many of us.

“Earlier on …

City University of New York (CUNY)

Why your brain acts like a jazz band

The human brain improvises while its rhythm section keeps up a steady beat. But when it comes to taking on intellectually challenging tasks, groups …

Scientific Research

A Sense Of Self: What Happens When Your Brain Says You Don't Exist

Science journalist Anil Ananthaswamy thinks a lot about "self" — not necessarily himself, but the role the brain plays in our notions of self and existence.

In his new book, The Man Who Wasn't There, Ananthaswamy examines the ways people think of themselves and how those perceptions can be distorted …

The Brain

Insulin resistance may boost risk of memory loss

The fact that obesity increases the risk of cardiovascular disease and some cancers is well known. A new study suggests that memory loss—and …

Dengue vaccine protects people nine years or older — but harms younger kids

A vaccine for dengue, a leading cause of illness and death among children in some Latin American and Asian countries, protects people nine years old and older from the infection, according to a study in the New England Journal of Medicine. There’s a catch, though: children vaccinated before age nine …

Kids

Milestone In Nigeria: One Year Polio-Free

It’s cause for excitement, but there’s more work ahead

One year ago today, health officials announced the last case of polio in Nigeria. Since then, the country has remained polio-free—one step of many toward an official certification of eradication from the World Health Organization.

As of 1988, …

Nigeria

New study shows yet another reason not to overuse antibiotics

Scientists have been warning for decades that we use too many antibiotics, both in people to treat relatively mild infections and in agriculture to bulk up farm animals and keep them free of disease.

The consequences, they caution, are dire—and already emerging in hospitals with bacteria that can’t …

Antibiotics

Software To Predict Exactly What Happens When You Edit A Gene

Sifting through the tangled genetic web of precision medicine

Genetics researchers are really excited about CRISPR/Cas9, an enzyme that has made it easier than ever for scientists to target a particular strand of DNA, snip part of it out, and replace it. And though its use in humans is still in its …

Life Sciences

'Gay genes': science is on the right track, we're born this way. Let’s deal with it.

In a recent Guardian article , Simon Copland argued that it is very unlikely people are born gay (or presumably any other sexual orientation). Scientific evidence says otherwise. It points strongly to a biological origin for our sexualities. Finding evidence for a biological basis should not scare …

Genetics

15 more memorable images from 15 years of the BMC-series - BMC Series blog

Snapshots of steady states in yeast mitotic spindles. From Head et al. 2011 BMC Biophysics “Spindles and active vortices in a model of confined …

Life Sciences

Chemistry World Blog » ISACS16 poster prize winner: Oliver Thorn-Seshold

— Oliver Thorn-Seshold

Chemistry World was delighted to sponsor a poster prize at ISACS16 (Challenges in Chemical Biology), held in Zurich, …

Chemistry

First malaria vaccine given green light by European regulators

The world’s first malaria vaccine has been given the green light by European regulators and could protect millions of children in sub-Saharan Africa from the life-threatening disease.

The European Medicines Agency (EMA) recommended that RTS,S, or Mosquirix, should be licensed for use in young …

Malaria Vaccine

Researchers decode molecular action of combination therapy for a deadly thyroid cancer

Posted by Kevin Punsky (@kevinpunsky) · 12 hour(s) ago

Researchers decode molecular action of combination therapy for a deadly thyroid …

Doctors are 'outraged' by the cost of cancer treatments

Recent breakthroughs in cancer treatment come with a hefty price tag.

In 2014, virtually every new cancer-treatment drug approved by the Food and Drug Administration was priced at more than $120,000 a year, according to a new study. And the cost for each additional year lived by a patient as a …

Cancer

Scientists are trying to make sense of a Native American link to indigenous Australians

Two new studies published this week in Natureand Science are battling it out over the true origins of Native American ancestry.

Both papers suggest contradictory interpretations of a new perplexing find: some remote populations living in the South American Amazon share a strong genetic connection with …

Indigenous Peoples

Genes influence academic ability across all subjects, latest study shows

You may feel you are just not a maths person, or that you have a special gift for languages, but scientists have shown that the genes influencing numerical skills are the same ones that determine abilities in reading, arts and humanities.

The study suggests that if you have an academic Achilles …

Science Education

To fend off dementia, run -- or dance, bike, power-walk or step

Scientists testing experimental drugs to prevent or reverse Alzheimer's disease have for years endured a drumbeat of inconclusive and disappointing trial results. But dementia researchers meeting in Washington, D.C., this week got some unexpectedly good news on the benefits of a therapy that is …

The Brain

Scientists find first drug that appears to slow Alzheimer's disease

Scientists appear to have broken a decades-long deadlock in the battle against Alzheimer’s disease after announcing trial results for the first drug that appears to slow the pace of mental decline.

The drug, called solanezumab, was shown to stave off memory loss in patients with mild Alzheimer’s …

Dementia

How nature's deadliest venoms are saving lives

(CNN) — They grow up to one meter in length and kill their prey using injections of venom.

Once the venom takes effect, victims black out from a drop in blood pressure, leaving them trapped and ready to be eaten -- head-first.

This is the feeding habit of the Brazilian pit viper, a snake found in the …

Medicine

Native American origins: When the DNA points two ways

This week, two teams of scientists released reports detailing the origins of Native American peoples. Both groups looked at ancient and modern DNA to attempt to learn more about the movements of populations from Asia into the New World, and about how groups mixed once they got here. Both discovered …

Ancient DNA