PLOS Pathogens Pearls on Flipboard

@PLOSPearls | 451 Articles | 7 Magazines | 458 Followers | PLOS Pathogens presents an Open Access compendium of "lessons-that-last." This living collection of short, educational, and highly useful articles addresses topics of relevance and importance within the wide-ranging field of pathogens research, with insights tailored to graduate students and post-docs.

Parasites and Their Heterophagic Appetite for Disease

by Vern B. Carruthers


Investigating Fungal Outbreaks in the 21st Century

1. Smith RM, Schaefer MK, Kainer MA, Wise M, Finks J, et al. (2013) Fungal infections associated with contaminated methylprednisolone injections. N …


Systems Biology for Biologists

Citation: Hillmer RA (2015) Systems Biology for Biologists. PLoS Pathog 11(5): e1004786. doi:10.1371/journal.ppat.1004786

Editor: Heather L. …

Life Sciences

Dust Devil: The Life and Times of the Fungus That Causes Valley Fever

1. Sharpton TJ, Stajich JE, Rounsley SD, Gardner MJ, Wortman JR, Jordar VS, et al. (2009) Comparative genomic analyses of the human fungal pathogens …


The Elusive Role of the Prion Protein and the Mechanism of Toxicity in Prion Disease

1. Malaga-Trillo E, Solis GP, Schrock Y, Geiss C, Luncz L, et al. (2009) Regulation of embryonic cell adhesion by the prion protein. PLoS Biol 7: …


Remembering Mumps

1. Dayan GH, Quinlisk MP, Parker AA, Barskey AE, Harris ML, Schwartz JM, et al. Recent resurgence of mumps in the United States. N Engl J Med. …


Ebola Virus Entry: A Curious and Complex Series of Events

1. Gire SK, Goba A, Andersen KG, Sealfon RS, Park DJ, Kanneh L, et al. (2014) Genomic surveillance elucidates Ebola virus origin and transmission …


The Ebola Epidemic Crystallizes the Potential of Passive Antibody Therapy for Infectious Diseases

1. Casadevall A, Scharff MD (1995) Return to the past: the case for antibody-based therapies in infectious diseases. Clin Infect Dis 21: 150–161. …

Infectious Diseases

Pathogens as Biological Weapons of Invasive Species

by Andreas Vilcinskas

Invasive Species

Antimicrobial-Induced DNA Damage and Genomic Instability in Microbial Pathogens

by Rebecca S. Shapiro


Catch Me If You Can: The Link between Autophagy and Viruses

by Nicholas J. Lennemann, Carolyn B. Coyne

Catch Me If You Can

To Be or Not IIb: A Multi-Step Process for Epstein-Barr Virus Latency Establishment and Consequences for B Cell Tumorigenesis

1. Epstein M, Achong B, Barr Y (1964) Virus particles in cultured lymphoblasts from Burkitt's lymphoma. Lancet 28: 702–703. doi: …


The Great Escape: Pathogen Versus Host

1. Akira S, Uematsu S, Takeuchi O (2006) Pathogen recognition and innate immunity. Cell Microbiol 124: 783–801. pmid:16497588 doi: …


Coping with Stress and the Emergence of Multidrug Resistance in Fungi

1. Brown GD, Denning DW, Gow NA, Levitz SM, Netea MG, et al. (2012) Hidden killers: human fungal infections. Sci Transl Med 4: 165rv113. doi: …

Drug Resistance

An Iron-Mimicking, Trojan Horse-Entering Fungi—Has the Time Come for Molecular Imaging of Fungal Infections?

1. Hayes GE, Denning DW (2013) Frequency, diagnosis and management of fungal respiratory infections. Curr Opin Pulm Med 19: 259–265. doi: …


A Case for Two-Component Signaling Systems As Antifungal Drug Targets

1. Pappas PG (2013) Lessons learned in the multistate fungal infection outbreak in the United States. Curr Opin Infect Dis 26: 545–550. doi: …


Bacterial Immune Evasion through Manipulation of Host Inhibitory Immune Signaling

1. Cohen J (2002) The immunopathogenesis of sepsis. Nature 420: 885–891. pmid:12490963

2. Zhu Y, Yao S, Chen L (2011) Cell surface signaling molecules …


Prions—Not Your Immunologist’s Pathogen

by Mark D. Zabel, Anne C. Avery

Immune System

Dimorphism in Fungal Pathogens of Mammals, Plants, and Insects

1. Bohse ML, Woods JP (2007) RNA interference-mediated silencing of the YPS3 gene of Histoplasma capsulatum reveals virulence defects. Infect Immun 75: …

Life Sciences

Telomeric ORFS in Candida albicans: Does Mediator Tail Wag the Yeast?

by Derek J. Sullivan, Judith Berman, Lawrence C. Myers, Gary P. Moran


Yeast Prions: Proteins Templating Conformation and an Anti-prion System

1. Wickner RB (1994) [URE3] as an altered URE2 protein: evidence for a prion analog in S. cerevisiae. Science 264: 566–569. pmid:7909170 doi: …


Livestock-Associated Staphylococcus aureus: The United States Experience

1. Weese JS (2010) Methicillin-resistant Staphylococcus aureus in animals. ILAR J 51: 233–244. doi: 10.1093/ilar.51.3.233.

2. McNamee PT, Smyth JA …

Helminth-Induced Immune Regulation: Implications for Immune Responses to Tuberculosis

1. WHO (2013) Global tuberculosis report 2013.​/91355/1/9789241564656_eng.pdf. Accessed 22 December 2014. …


Implication of Gut Microbiota in Nonalcoholic Fatty Liver Disease

1. Wiest R, Garcia-Tsao G (2005) Bacterial translocation (BT) in cirrhosis. Hepatology 41: 422–433. doi: 10.1002/hep.20632. pmid:15723320

2. Weinstock …


The Shear Stress of Host Cell Invasion: Exploring the Role of Biomolecular Complexes

1. Hansson GC (2012) Role of mucus layers in gut infection and inflammation. Curr Opin Microbiol 15: 57–62. doi: 10.1016/j.mib.2011.11.002.

2. Davies …


Malassezia Infections in Humans and Animals: Pathophysiology, Detection, and Treatment

1. Findley K, Oh J, Yang J, Conlan S, Deming C, et al. (2013) Topographic diversity of fungal and bacterial communities in human skin. Nature 498: …

Virus-Induced NETs – Critical Component of Host Defense or Pathogenic Mediator?

by Craig N. Jenne, Paul Kubes


Unique Features of HIV-1 Spread through T Cell Virological Synapses

by Raymond A. Alvarez, Maria Ines Barría, Benjamin K. Chen

Life Sciences

Brothers in Arms: Th17 and Treg Responses in Candida albicans Immunity

1. Hernández-Santos N, Gaffen SL (2012) Th17 cells in immunity to Candida albicans. Cell Host Microbe 11: 425–435. doi: 10.1016/j.chom.2012.04.008

2. …