PLOS Ebola Collection

By PLOS Collections | There is an urgent need for research into all aspects of this Ebola outbreak. PLOS is addressing this need today through two channels. First is the rapid publication of important early research in PLOS Currents Outbreaks. The second is a new PLOS Collection that pulls together all the current published articles in the PLOS corpus, which are, like all our content, freely and openly available for download, use and reuse.

Ebola Cases and Health System Demand in Liberia

Abstract<p>In 2014, a major epidemic of human Ebola virus disease emerged in West Africa, where human-to-human transmission has now been sustained for …

Ebola

Characterizing the Transmission Dynamics and Control of Ebola Virus Disease

1. Briand S, Bertherat E, Cox P, Formenty P, Kieny MP, et al. (2014) The international Ebola emergency. N Engl J Med 371: 1180–1183. doi: …

How Will the Ebola Epidemic End?

Upon his return from 6 weeks volunteering with the King’s Sierra Leone Partnership at a number of Ebola isolation facilities in Freetown, Tom Boyles …

Ebola

Publishing to Keep up with Ebola

As you read this, thread-like viruses less than one micron in length are spreading through human populations in West Africa, taking lives, wrecking …

Projected Impact of Vaccination Timing and Dose Availability on the Course of the 2014 West African Ebola Epidemic

Introduction<p>The 2014 West African Ebola epidemic has evolved into a human catastrophe of historical proportions 1 ; as of October 22, 2014, nearly …

Assessment of the Risk of Ebola Importation to Australia

Introduction<p>The largest outbreak of Ebola virus ever recorded continues to spread in West Africa. In response, the World Health Organisation (WHO) …

Ebola and Indirect Effects on Health Service Function in Sierra Leone

Introduction<p>Ebola Viral Disease (EVD) continues to ravage Sierra Leone. Experts have expressed concerns of complete breakdown in civic society.1 To …

Is West Africa Approaching a Catastrophic Phase or is the 2014 Ebola Epidemic Slowing Down? Different Models Yield Different Answers for Liberia

Commentary<p>An unprecedented epidemic of Zaire ebolavirus (EBOV) has affected West Africa since approximately December 2013, with intense transmission …

Shed GP of Ebola Virus Triggers Immune Activation and Increased Vascular Permeability

1. Baize S, Pannetier D, Oestereich L, Rieger T, Koivogui L, et al. (2014) Emergence of Zaire Ebola Virus Disease in Guinea - Preliminary Report. N …

Biology

A Three-Scale Network Model for the Early Growth Dynamics of 2014 West Africa Ebola Epidemic

Introduction<p>As of mid-October 2014, the number of reported suspected cases of the Ebola epidemic in West Africa had exceeded 9,000 cases, which is …

Ebola

What Factors Might Have Led to the Emergence of Ebola in West Africa? | Speaking of Medicine

<b>The below manuscript was initially posted here on November 11th, 2014 following its conditional acceptance by PLOS Neglected Tropical Diseases for</b> …

The UCSC Ebola Genome Portal

Introduction<p>The Ebola epidemic continues to grow in West Africa. The U.S. Centers for Disease Control (CDC) estimated the occurrence of 21,000 cases …

Africa

Social Pathways for Ebola Virus Disease in Rural Sierra Leone, and some Implications for Containment | Speaking of Medicine

<b>The below manuscript was initially posted here on October 31st, 2014 following its conditional acceptance by PLOS Neglected Tropical Diseases for</b> …

Ebola has Taught us a Crucial Lesson about our Views of “Irrational” Health Behaviors | Speaking of Medicine

<b>Sara Gorman compares “irrational” reactions to the Ebola outbreak by Americans and West Africans.</b><p>As Ebola rears its ugly head in the U.S., there has …

Modeling the Impact of Interventions on an Epidemic of Ebola in Sierra Leone and Liberia

Introduction<p>West Africa is currently experiencing an unprecedented outbreak of Ebola, a viral hemorrhagic fever. On March 23, 2014 the World Health …

On the Quarantine Period for Ebola Virus

Introduction<p>For contagious diseases, to reduce the spread, it is necessary and desirable to quarantine each individual who might have been exposed …

Insights into the Early Epidemic Spread of Ebola in Sierra Leone Provided by Viral Sequence Data

Introduction<p>The 2014 West African Ebola virus (EBOV) epidemic is the largest Ebola virus outbreak to date with 7492 cases (4108 confirmed) and 3439 …

Commentary: Containing the Ebola Outbreak – the Potential and Challenge of Mobile Network Data

Appendix 1<p><b>Containing the Ebola outbreak - the potential and challenge of mobile network data: Appendix 1</b><p><i>Materials and Methods</i><p>We analyzed a number of …

Ebola: a Blind Outbreak | Speaking of Medicine

<b>Grazia Caleo of Médecins Sans Frontières (MSF) UK describes her experiences as a medical epidemiologist during the Ebola outbreak in Kailhun, Sierra</b> …

Early Epidemic Dynamics of the West African 2014 Ebola Outbreak: Estimates Derived with a Simple Two-Parameter Model

Introduction<p>Ebola virus is a zoonotic filovirus that causes a hemorrhagic fever syndrome in humans, with a high case-fatality rate 5. An epidemic …

Temporal Variations in the Effective Reproduction Number of the 2014 West Africa Ebola Outbreak

Introduction<p>Ebola virus disease (EVD) is a severe, often fatal viral infection in humans, with a case fatality risk (CFR) of up to 90% in previous …

Speaking of Medicine

<b>Virginia Barbour, Medicine & Biology Editorial Director at PLOS, on the urgent need for Open Access research into the Ebola outbreak in West …

Assessing the International Spreading Risk Associated with the 2014 West African Ebola Outbreak

Introduction<p>The outbreak of Ebola virus disease (EVD) that started in December 2013 has defied several months of mitigation and containment efforts. …

Estimating the Reproduction Number of Ebola Virus (EBOV) During the 2014 Outbreak in West Africa

Introduction<p>The 2014 Ebola virus (EBOV) outbreak in West Africa is the largest outbreak of the genus <i>Ebolavirus</i> to date. The outbreak began in Guinea …

The Global Response to the Ebola Fever Epidemic: What Took So Long? | Speaking of Medicine

<b>Mark J. Siedner of Harvard Medical School and John D. Kraemer of the O’Neill Institute for National and Global Health Law, Georgetown University,</b> …

Ebola: Liberians Destined for Extinction | Speaking of Medicine

<b>Liberian medical student Gondah Lekpeh gives us his perspective from the front lines of the Ebola outbreak.</b><p>On July 22 of this year, the Liberian …

Outbreak of Ebola Virus Disease in Guinea: Where Ecology Meets Economy

<b>Citation:</b> Bausch DG, Schwarz L (2014) Outbreak of Ebola Virus Disease in Guinea: Where Ecology Meets Economy. PLoS Negl Trop Dis 8(7): e3056. …

Ebola

Phylogenetic Analysis of Guinea 2014 EBOV Ebolavirus Outbreak

Introduction<p>A recent article1 suggests that the currently ongoing outbreak in Guinea is caused by a divergent variant of the Zaire ebola (EBOV) …

Clock Rooting Further Demonstrates that Guinea 2014 EBOV is a Member of the Zaïre Lineage

Introduction<p>Phylogenetic analyses are a very popular and powerful way to extract information from sequences. The end product is a tree-like graph …