Paul Denny

33 Flips | 4 Magazines | 2 Likes | 1 Following | 20 Followers | @pauldennyuk | Keep up with Paul Denny on Flipboard, a place to see the stories, photos, and updates that matter to you. Flipboard creates a personalized magazine full of everything, from world news to life’s great moments. Download Flipboard for free and search for “Paul Denny”

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35 Random Corners Of The Internet You Should Visit When You Need A Break

Bookmark this for when you're having a bad day or when you just need a distraction and want to play. There's something so soothing about these single-serving sites.<p>Major h/t to this post by Tumblr user Writing Weasels and the website The Useless Web for providing me with endless hours of amusement.

Jackson Pollock

Measuring gene functional similarity based on group-wise comparison of GO terms | Bioinformatics | Oxford Academic

A graph-based semantic similarity measure for the gene ontology<p>Ontology-driven similarity approaches to supporting gene functional assessment<p>An …


The interaction between Lactoferrin and LPS

LACTOFERRIN<p><b>Lactoferrin (LF)</b> Lactoferrin (Lf), first reported almost 50 years ago (and referred as "red milk protein") is a non-hemic iron-binding …


PDBnet ( Domain information page )

PDBnet ( Chain information page )

PDBnet ( Cluster information page )

PDBnet ( Biochemical PPI information page )

Unlocking the Mysteries of Extracellular RNA Communication

Innate Immunity: Viral Pathogen Immune Response - IMGENEX

Immune Response, Toll Like Receptors (TLR) Pathway - IMGENEX

Julie Theriot (Stanford) Part 1: Cell Motility (archive)

Host-Pathogen Interactions in Streptococcus pneumoniae

The Triple Bottom Line: What Is It and How Does It Work?

<b>Director of Economic Analysis,</b> Indiana Business Research Center, Indiana University Kelley School of Business<p><b>Economic Research Analyst,</b> Indiana …

ChIPXpress: using publicly available gene expression data to improve ChIP-seq and ChIP-chip target gene ranking

ChIPXpress is able to improve upon the ChIPx-only rankings<p>In order to evaluate ChIPXpress, we analyzed 10 ChIP-seq, ChIP-chip promoter array, and …

Data Science

Comparing somatic mutation-callers: beyond Venn diagrams

TCGA benchmark studies generated mutation-calling outputs by applying multiple callers on the same sequence alignments (BAMs [22]) for a selected …

KNODWAT: A scientific framework application for testing knowledge discovery methods for the biomedical domain

This section presents a feature list of the completed KNODWAT framework as well as a small knowledge discovery study using two biomedical data sets, …

Machine Learning

Quantifying single nucleotide variant detection sensitivity in exome sequencing

Background<p>The targeted capture and sequencing of genomic regions has rapidly demonstrated its utility in genetic studies. Inherent in this technology …


SeqSIMLA: a sequence and phenotype simulation tool for complex disease studies

Background<p>Association studies based on next-generation sequencing (NGS) technology have become popular, and statistical association tests for NGS …


Using ancestral information to detect and localize quantitative trait loci in genome-wide association studies

Background<p>In mammalian genetics, many quantitative traits, such as blood pressure, are thought to be influenced by specific genes, but are also …


Prediction of gene-phenotype associations in humans, mice, and plants using phenologs

A matrix-based formalism for comparing gene-phenotype associations between species<p>The phenolog approach, developed by McGary et al. in [9], …

A unifying perspective on pathogen specificity

Linking microevolutionary processes to macroevolutionary patterns<p>I have always been interested coevolutionary interactions, particularly …

From infection to detection: imaging S. aureus--host interactions

<b>U. Neugebauer , C. Grosse , M. Bauer , B. Kemper , A. Barroso-Pena and A. Bauwens</b><br>Infections, particularly those due to drug-resistant pathogens, …


.<br>Bats Host More Than 60 Human-Infecting Viruses<br>By Joseph Castro, LiveScience Contributor | – Wed, Feb 6, 2013.<p>Many animals harbor viruses that can jump to other species, but bats may be in a class of their own when it comes to carrying zoonotic (human-infecting) viruses. Bats are reservoirs for more than 60 viruses that can infect humans, and host more viruses per species than even rodents do, new research shows. <br>"There seems to be something different about bats in terms of …

Chimps and humans share another evolutionary link: gut bacteria

<b>Chimps and humans share another evolutionary link: gut bacteria</b><p><i>In the last few years, scientists have made great inroads in understanding the crucial interactive role gut bacteria play in harvesting nutrients, assisting immune systems, and protecting the host against pathogens.</i><p><i>Now Yale University researchers have discovered that humans and chimpanzees, our closest evolutionary relatives, share the same three distinct communities, or ecosystems, of bacteria in their guts.</i><p><i>“This shared</i> …