Pharma readings

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Teva Pharmaceutical reportedly set for major layoffs in Israel and the US

The world's largest generic drugmaker will send termination letters to "tens of percents" of its 10,000 employees in the United States in coming …

Scientific Research

That Time A Researcher Wished His Brain Tumor Had A Share Button

As preparation for the Forbes Healthcare Summit next week, I’ve been going through past presentations. This one, from 2015, is one of my all-time favorites.<p>In 2007, Steven Keating, then an MIT postdoc, volunteered for a research study that involved an MRI of a brain. Researchers found an …

Cancer

J&J multiple myeloma drug succeeds in first-line combination study

(Reuters) - Johnson & Johnson's blockbuster multiple myeloma drug Darzalex when added to a standard therapy regimen reduced the risk of disease progression or death by 50 percent compared with the standard therapy alone in patients not previously treated for the blood cancer, according to data …

Cancer

Under pressure in diabetes, Novo Nordisk steps up focus on obesity drugs

MÅLØV, Denmark (Reuters) - Danish drugmaker Novo Nordisk is stepping up its efforts to treat obesity, seeking to tap into a potentially huge market as its established diabetes drugs come under price pressure, particularly in the United States.<p>The world's largest maker of diabetes drugs said on …

Diabetes

Fighting Cancer One Patient At A Time

Allan Brandt, a 63-year-old history of medicine professor at Harvard, seems taken aback to have become part of medical history himself. In 2012, he was diagnosed with acute myeloid leukemia, a deadly cancer that had a potential cure: a bone marrow transplant. His sister was a match, and he went …

Cancer

Roche Cancer Drug Rises To Challenge Merck, Bristol-Myers

Tecentriq, a cancer immunotherapy developed by the Swiss drug giant Roche, slowed the progression of previously untreated lung cancer in a large clinical trial when combined with a chemotherapy regimen, the drug giant said.<p>“We are extremely encouraged by these results and will submit these data to …

Cancer

EMA round 1: Amsterdam, Copenhagen, and Milan fight for EU agency

Ding ding. The first round is done.<p>Milan, Amsterdam and Copenhagen have made it through to the second round of voting in Brussels in a contest to …

Copenhagen

The drug-maker's guide to the galaxy

How machine learning and big data are helping chemists search the vast chemical universe for better medicines.<p>In 2016, the pharmaceutical firm …

Machine Learning

Roche says Tecentriq combination cuts lung cancer risk

ZURICH (Reuters) - Roche got a double dose of positive trial news on Monday, with its immunotherapy Tecentriq mixed with other drugs succeeding against lung cancer in one study and its haemophilia drug Hemlibra notching a win in a new group of patients.<p>With lung cancer easily the largest oncology …

Cancer

Pfizer, Novartis agree UK price cuts for new breast cancer drugs

LONDON (Reuters) - Pfizer and Novartis have agreed price cuts for their rival breast cancer drugs Ibrance and Kisqali to ensure they can be used routinely within Britain's state-funded health service.<p>The National Institute for Health and Care Excellence (NICE), the country's cost-effectiveness …

Cancer

Gene Editors, Cancer Killers And Smartphone Apps: The 2018 30 Under 30 In Healthcare

The drug business has long been allergic to youth. But take a look at this year’s 30 Under 30 in healthcare, and you’ll see that’s starting to change.<p>Take Leah Sibener and Marvin Gee, both 26, who were working in the laboratory of Stanford biologist Chris Garcia when they developed the foundation …

Martin Shkreli

Boehringer claims EU okay for Humira biosimilar

<b>Boehringer Ingelheim has picked up its first EU approval for a biosimilar drug, getting a green light from the EMA for its version of AbbVie’s</b> …

Pharma

Biotech firms race to recruit good bugs in war on cancer

(Reuters) - Biotech companies are competing to develop medicines using "bugs as drugs" to fight cancer, building on the latest scientific findings that patients with high levels of good gut bacteria are more likely to respond to modern immunotherapy.<p>Certain bacteria seem to help in cancer by …

Microbiome

FDA approves AstraZeneca's asthma drug

(Reuters) - Anglo-Swedish pharmaceutical firm AstraZeneca Plc on Tuesday said the U.S. Food and Drug Administration approved its drug benralizumab, as an add-on treatment for patients with severe asthma aged 12 years and older.<p>The asthma drug will be marketed under the name Fasenra in the United …

Medicine

Loxo, Bayer to co-develop cancer drugs in up to $1.55 billion deal

(Reuters) - Loxo Oncology Inc will collaborate with Germany's Bayer AG to develop and commercialize two of its cancer therapies, the companies said on Tuesday, in deal that could bring the U.S. drug developer up to $1.55 billion.<p>The drugs - larotrectinib and follow-on compound LOXO-195 - are TRK …

Cancer

Novartis launches heart drug counter-offensive

ZURICH (Reuters) - Novartis plans to plow through doubts over its canakinumab drug by asking regulators this year to approve the medicine as a treatment for a group of heart attack survivors that the Swiss drugmaker says is most likely to benefit.<p>New analysis of Phase III data shows canakinumab cut …

Medicine

FDA Approves First Digital Pill That You (And Others) Can Track

“Did you take that pill?’<p><b>Response:</b> “Yes.”<p>“Are you sure?”<p><b>Response:</b> “Absolutely. I’m fairly certain. I think so. Maybe. What was your question again?”<p>“Let’s ask the pill.”<p>Today the Food and Drug Administration (FDA) announced that they approved the first drug in the U.S. that can tell you and others …

Pharma

Microsoft founder Gates commits $100 million for fund, start-ups, to fight Alzheimer's

LONDON (Reuters) - Billionaire Microsoft co-founder Bill Gates is to invest $50 million in the Dementia Discovery Fund, a venture capital fund that brings together industry and government to seek treatments for the brain-wasting disease.<p>The investment is not part of Gates' philanthropic Bill & …

Dementia

Pfizer exits China joint venture for generic drugs

(Reuters) - Pfizer Inc (PFE.N) said on Friday it has sold its 49 percent stake to exit a joint venture it had set up with China’s Zhejiang Hisun Pharmaceuticals (600267.SS) in 2012 to develop and market generic drugs.<p>FILE PHOTO: The Pfizer logo is seen at their world headquarters in New York April …

China

Roche Gains Positive CHMP Opinion for MS Drug

Roche Holding AG (RO.EB) said Friday that a European Medicines Agency committee gave a positive opinion on its multiple-sclerosis drug, marking an important step toward EU approval.<p>The Committee for Medicinal Products for Human Use, or CHMP, recommended a marketing authorisation be granted for …

Medicine

AstraZeneca rides China wave as rival GlaxoSmithKline struggles

LONDON (Reuters) - AstraZeneca (AZN.L) is enjoying booming drug sales in China, helped by reforms to the country's regulatory system and an increased sales force, in sharp contrast to its British rival GlaxoSmithKline (GSK.L).<p>China revenue in the third quarter increased by 12 percent at AstraZeneca …

Pharma

AstraZeneca sales decline slows as it waits for medicine to work

AstraZeneca's drug sales fell again in the third quarter, hit by generic competition to former blockbusters like cholesterol pill Crestor, although …

Markets

Novartis strengthens autoimmune indications for Cosentyx

Data shows its IL-17A inhibitor can reduce structural disease progression

Pharma

AstraZeneca brightens forecasts as sales decline slows

AstraZeneca said its profits are unlikely to fall as far as previously feared this year, after the decline in sales of its older drugs slowed in the …

Markets

GlaxoSmithKline appoints Hal Barron as R&D chief

, Global Pharmaceuticals Editor<p>Emma Walmsley has taken the next step in reshaping GlaxoSmithKline’s R&D operation by appointing Hal Barron, a …

Medicine

Six Ways Amazon Could Up-End the Pharmacy Business

The pharmacy market is one of the biggest potential new targets for Amazon.com Inc.<p>In June, the online retail giant moved into the roughly $800 …

Pharma

Court demands that search engines and internet service providers block Sci-Hub

American Chemical Society awarded $4.8 million in damages from site with millions of illegally hosted journal papers

Copyright

Novartis cancer drug Kisqali succeeds in late-stage trial

ZURICH (Reuters) - Novartis drug Kisqali was shown effective in a late-stage trial in treating advanced or metastatic breast cancer, the Swiss drugmaker said on Wednesday.<p>In the so-called MONALEESA-7 trial, Kisqali (ribociclib) combination therapy met its primary endpoint of progression-free …

Cancer

Bayer in bid to broaden use of anti-clotting drug Xarelto

FRANKFURT (Reuters) - German drugmaker Bayer on Monday moved to tap a potentially lucrative new market opportunity for its blockbuster clot prevention drug Xarelto, requesting approval in Europe to make atherosclerosis patients eligible for treatment.<p>Xarelto is already approved for a number of …

Medicine