Mary York

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Analysis of diet-induced differential methylation, expression, and interactions of lncRNA and protein-coding genes in mouse liver

1.<p>Carninci, P. <i>et al</i>. The transcriptional landscape of the mammalian genome. <i>Science</i> <b>309</b>, 1559–1563 (2005).<p>2.<p>Djebali, S. <i>et al</i>. Landscape of …

Establishment of environmentally sensitive DNA methylation states in the very early human embryo

• H. Okae,<br>• H. Chiba,<br>• H. Hiura,<br>• H. Hamada,<br>• A. Sato,<br>• T. Utsunomiya,<br>• H. Kikuchi,<br>• H. Yoshida,<br>• A. Tanaka,<br>• M. Suyama,<br>• T. Arima<p>, Genome-wide analysis of DNA methylation …

Meet the 29-year-old who founded a company that's using technology to find treatments for diseases thought to be incurable

The drug development process is laden with problems that make it lengthy and expensive. Right now, it takes 12 years and $2.6 billion to get a single drug to market, with the drug discovery and development process costing $1.4 billion.<p>Verge Genomics, run by 29-year-old Alice Zhang, is trying to …

Machine Learning

Researchers discover why the CRISPR gene editing system sometimes fails

The CRISPR gene editing revolution is less than a decade old and scientists are still learning how best to deploy this ground-breaking technique. A …

CRISPR Makes Cancer Cells Turncoats That Attack Their Tumor

As an idea for wiping out cancer, it could have been ripped from the pages of a spy thriller: Take cancer cells that have departed the original tumor …

Scientists reprogram T Cells to target autoimmune diseases

Researchers from the University of California, San Francisco have uncovered a gene-editing technique which could provide safer treatments for patients with cancer and autoimmune diseases. The breakthrough -- which involves the CRISPR/Cas9 system -- will allow T cells (the cells which fire up our …

Immunotherapy

New Drugs May Stop Migraines Before They Start

Health news<p>For 63-year-old Lynn Kaufman, the battle against migraines consumed her life. Since she was 12-years-old, she'd experienced paralyzing pain three to four times a week — each year worse than the one before.<p>“It felt as though my head was a cement block,” Kaufman told NBC News. “It hurt to …

Los Angeles

Vespa's new robot will carry your groceries

Vespa, best known for its stylish scooters, is trying something new.<p>The Italian company is opening a Boston-based division, called Piaggio Fast Forward, to focus on the future of mobility. Its first creation is Gita, a robot designed to carry cargo, such as groceries, and follow around a pedestrian …

Robotics

First Genetic Results From Scott Kelly's Year In Space Reveal DNA Mysteries

After recent events, we’re all ready to hop aboard the next flight to Mars. But before us Earthlings embark on a seven-month journey to the Red …

Autism study shows benefits when parents get involved

<b>(CNN) —</b> For millions of families around the world, autism poses daily challenges. Some parents find it difficult or even impossible to communicate with their own children or understand how they perceive the world around them. This mental condition can also affect their child's ability to interact …

Fertility experts urge UK to adopt new DNA screening for IVF embryos

Mitochondrial DNA quantification could help doctors select embryos with the best of chance of leading to a pregnancy, research shows<p>A new technique to genetically screen IVF embryos should be considered for use in the UK, fertility experts say. The call comes after research revealed it could help …

Can you get Zika twice? Or are you immune?

<b>(CNN) —</b> Once you've had Zika, can you get it again? Scientists don't think so, but it's never been proved. Researchers from the University of Wisconsin say they are one step closer to answering that question after studying how the virus affects rhesus macaque monkeys.<p>"It's important for us to show …

IBM's Watson may provide a shortcut to treating cancer

Here's a question IBM supercomputer Watson never got to ask on "Jeopardy": What is a cure for cancer?<p>Watson, best known for beating champions Ken Jennings and Brad Rutter on the game show, will get its chance as it aids scientists using analysis of gene structures to figure out the cause of and …

WhoApp promises to take the guesswork out of who's calling

Is the unknown number calling you the cute guy you met last night? Or an annoying telemarketer?<p>WhoApp, a new iPhone app, promises to take the dice roll out of picking up that call.<p>Developed by New Jersey's TelTech, WhoApp recognizes calls from telemarketers, scammers and even annoying acquaintances …

Your brain does not process information and it is not a computer – Robert Epstein

No matter how hard they try, brain scientists and cognitive psychologists will never find a copy of Beethoven’s 5th Symphony in the brain – or copies …

Singularity

You Sigh Without Realizing It Every Five Minutes. Here's Why.

Scientists pinpoint two clusters of neurons in the brain responsible for sighing.<p>We sigh when we're stressed, when we're in love and when we practice yoga and meditation -- but that's not all. Our brains signal for us to sigh every five minutes, often without us even realizing it. (Seriously, …

Indian minister calls for mandatory foetal gender tests

India's children's minister has called for mandatory tests to determine the sex of an unborn child in an effort to counter high levels of female foeticide.<p>But women's rights activists have described her suggestion as "shocking" and say legalising the tests would only increase the problem.<p>Male …

How Alphabet became the biggest company in the world

Photograph: Manu Fernandez/AP<p>Google’s chief executive Sundar Pichai.<p>84<p>image/jpeg<p>https://media.guim.co.uk/fd9b9ed4d416bd1867fe356e49975b9527c26765/0_0_2588_1551/140.jpg<p>140<p>Photograph: Paul Sakuma/AP<p>Google’s co-founders Larry Page and Sergey …

Marissa Mayer

Georgia executes oldest death row inmate for 1979 murder

ATLANTA (Reuters) - A 72-year-old man convicted of murdering a convenience store manager in a 1979 robbery in Atlanta’s suburbs was executed in Georgia early on Wednesday, corrections officials said.<p>Georgia's oldest death row inmate, 72-year-old Brandon Astor Jones, is shown in this undated handout …

Day School GIF

Discover & share this Day GIF with everyone you know. GIPHY is how you search, share, discover, and create GIFs.

Quick Desserts to Whip Up in Less than 30 Minutes

Our new favorite (gluten-free!) chocolate chip cookie requires only five ingredients and 25 minutes, start to finish.

Dessert

An octopus senses light with its skin

New research shows an octopus can change skin color in response to light, without input from the eye or brain.<p>Well known for their intelligence, …

University of California

This Smart Parachute Wants To Save Your Drone From Disaster

An automated safety system for automated flyers<p>The worst part of having a drone is losing it. Pilots will go to great lengths to make sure their drones stay clear of harm, whether it’s diving into a canal to save it from drowning or turning a mishap on national television into a learning experience …

Meet The Machine That Could Replace Anesthesiologists

It can only be used for simple procedures for now, but that's changing quickly<p>Say hello to the hunk of plastic that could replace your anesthesiologist.<p>Right now, only four U.S. hospitals are using the Sedasys anesthesiology machine to sedate patients before surgery. Johnson & Johnson has been …

Johnson & Johnson

What would you see in a black hole?

What would it be like to fly a spacecraft into a black hole? Marcus Woo investigates.<p>Something about a black hole just pulls you in. Sure, its gravity is so strong that not even light can elude its grasp. But, there's something else, something harder to pinpoint. Maybe it's a black hole's absolute …

Boko Haram stoned Nigerian girls to death as rescuers approached

With rescue near, Nigerian girls, women stoned to death by Boko Haram, three blown up by landmine<p><b>Boko Haram</b> fighters stoned their captives to death as rescuers approached, while other girls and women held by the jihadists were crushed by an armoured car and killed by an exploding landmine as they …

Einstein's election riddle: are you in the two per cent that can solve it?

Last month I blogged about a logic puzzle that had gone viral in Singapore. My posts on Cheryl’s birthday problem attracted more readers than anything I have ever written before: more than five million views. For a couple of days they were the most popular stories across the entire Guardian website.<p>…

The USGS Is Mapping Human-Caused Earthquake Hazards

Earthquake mapping reveals humans can actually cause earthquakes.<p>Just days after Oklahoma's government embraced the idea that human actions could, in fact, cause earthquakes, the United States Geological Survey (USGS) released a report outlining how they could potentially provide earthquake mapping …

Natural Disasters

A five-step guide to not being stupid

Even the smartest people can be fools. David Robson explains how to avoid the most common traps of sloppy thinking.<p>If you ever doubt the idea that the very clever can also be very silly, just remember the time the smartest man in America tried to electrocute a turkey. Benjamin Franklin had been …

Open-Mindedness