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Miniaturization of Two-Photon Microscopy for Imaging in Freely Moving Animals

• Fritjof Helmchen,<br>• Winfried Denk and<br>• Jason N.D. Kerr<p>Adapted from <i>Imaging in Neuroscience</i> (ed. Helmchen and Konnerth). CSHL Press, Cold Spring Harbor, NY, …

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Metabolic Pitfalls of CNS Cre-Based Technology

Nestin-Cre mice have a significant metabolic phenotype that is hard to discern from current literature. Indeed, the Cre-lox system has numerous …

Metabolic Regulation by p53 Family Members

The function of p53 is best understood in response to genotoxic stress, but increasing evidence suggests that p53 also plays a key role in the …

CSHAsia 2013 Conference on New Advances in Optical Imaging of Live Cells and Organisms

Neuroscience thinks big (and collaboratively)

Abstract<p>Despite cash-strapped times for research, several ambitious collaborative neuroscience projects have attracted large amounts of funding and …

Neuroscience

How to: make a microscope from a webcam

Mark Miodownik, presenter from Dara O Briain's Science Club on BBC Two, reveals how you can perform simple science experiments at home. Try some DIY science and see the microscopic world up close by turning a webcam inside out...<p>Create a high-powered microscope from a cheap webcam by following …

New high-tech laser method allows DNA to be inserted 'gently' into living cells

Technique offers greater-than-ever control of essential gene therapy and genetic engineering method<p>WASHINGTON, Aug. 7--The applications of gene …