Henk van Kranen

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Cardiovasculaire risicoreductie met PCSK9-remming

Waarom dit onderzoek?Remming van het enzym proproteïneconvertase subtilisine-kexine type 9 (PCSK9) geeft een reductie van ongeveer 60% van het …

How structural biology can help rescue diabetic hypoglycemia @Nature succinct translation of 4 GLP-1/GCGR papers in current issue #diabetes https://t.co/Kp4u521vHH

Eén op de drie Nederlanders gebruikt elektronisch hulpmiddel bij sport en bewegen

Eén op de drie Nederlanders – 4,1 miljoen personen van 18 jaar of ouder – gebruikt elektronische hulpmiddelen bij sport en bewegen, zoals apps,</i> …

gnomAD browser

Downloads<p>Genome Aggregation Database (gnomAD) data are available at the links below. Please see this blog post for more information about this …

Leptin decreases the expression of low-density lipoprotein receptor via PCSK9 pathway: linking dyslipidemia with obesity. - PubMed

BACKGROUND:<p>Previous studies have suggested that people with obesity showed elevated serum levels of leptin as well as lipid dysfunction and …

Hoe de mediacratie haar eigen treitervloggers baart

Het nieuwe geweld is mediageweld.<p>De treitervloggers uit Zaandam zijn al weken niet uit de krant en van het scherm te slaan. De nieuwsdynamiek …

Precision medicine the theme at world's biggest cancer conference

New era of targeted treatment that will extend survival rates detailed at American Society of Clinical Oncology meeting<p>A new era of cancer treatment is beginning in which patients get drugs matched specifically to their tumour, according to scientists at the world’s biggest cancer conference in …

Cancer

Educate Your Immune System

IN the last half-century, the prevalence of autoimmune disease — disorders in which the immune system attacks healthy tissue in the body — has increased sharply in the developed world. An estimated one in 13 Americans has one of these often debilitating, generally lifelong conditions. Many, like …

Microbiology

The 100 000 Genomes Project

• Mark Peplow, freelance journalist, Cambridge<p>peplowscience{at}gmail.com<p>Part research project, part commercial stimulus, this enormous sequencing …

Genetics

Signatures of early frailty in the gut microbiota

Abstract<p>Background<p>Frailty is arguably the biggest problem associated with population ageing, and associates with gut microbiome composition in …

Biology

Alfa Romeo dealer Wim Prins - Nunspeet

Alfa nieuws<p>21.02.2018<p>Toen in november vorig jaar bekend werd dat Alfa Romeo...<p>06.10.2017<p>We kunnen er de hele dag naar kijken: de Alfa …

Rapid metagenomic identification of viral pathogens in clinical samples by real-time nanopore sequencing analysis.

2015 Sep 29;7:99. doi: 10.1186/s13073-015-0220-9.<p>1Department of Laboratory Medicine, University of California, San Francisco, CA, 94107, …

Introducing Genomics in Healthcare

Feature: A controversial company offers a new way to make a baby

A controversial fertility company called OvaScience is preoccupied by an enduring mystery in human biology—why eggs fail—and the palpable hope that …

Genetics

Dealing with the Genomics and Health Information Overload: Introducing the CDC Public Health Genomics Knowledge Base

Understanding genetic information is increasingly becoming important for health decision making for a variety of health conditions across the …

Genetics

Is It Really Only $1,000 to Sequence a Genome? - MIT Technology Review

It cost $2.7 billion to sequence the first human genome, which was completed in 2003. But even then scientists talked about it someday being possible …

Genetics

Use of metabotyping for the delivery of personalised nutrition. - PubMed

SCOPE:<p>Personalised nutrition can be defined as dietary advice that is tailored to an individual. In recent years, the concept of targeted nutrition …

Recensie Het gezonde lifestyleboek

<i>Het gezonde lifestyleboek</i> van Ivan Wolffers heeft als ondertitel ‘Hoe we tien jaar aan ons leven kunnen toevoegen’. Je zou denken dat dit één van de …

Dietary lipids modulate the expression of miR-107, an miRNA that regulates the circadian system. - PubMed

SCOPE:<p>The increased prevalence of cardiovascular diseases (CVDs) has been hypothesized to be the result of an increased exposure to a host of …

ExAC: It’s BIG and easy to use – Barrett Group

<i>There’s a new genomic database in town and everyone should know about it.</i><p>As humans, we are each different. With the exception of the majority of …