Gareth Price

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Mutations in sodium-channel gene SCN9A cause a spectrum of human genetic pain disorders

The voltage-gated sodium-channel type IX α subunit, known as Nav1.7 and encoded by the gene SCN9A, is located in peripheral neurons and plays an …

Huwentoxin-IV: a voltage-gated sodium channel blocker

Product code: N/A. Category: Sodium channels. Tags: nav, tetrodotoxin.<p>AA sequence: …

US8183221B2 - Suppression of SCN9A gene expression and/or function for the treatment of pain

CROSS REFERENCE TO RELATED APPLICATIONS<p>This application is an application under section 371 of International Patent Application No. PCT/US2008/075409 …

Pain killers

You might not like it, but you need to feel pain. It’s important. It helps to keep you safe by letting you know when something is wrong. You …

Deadly snake venom delivers pain relief

Proteins from the black mamba could inspire painkilling drugs.<p>With a series of swift bites, the black mamba injects a toxic cocktail that can kill a …

ProTx-II, a Selective Inhibitor of NaV1.7 Sodium Channels, Blocks Action Potential Propagation in Nociceptors

Ahmad S, Dahllund L, Eriksson AB, Hellgren D, Karlsson U, Lund PE, Meijer IA, Meury L, Mills T, Moody A, Morinville A, Morten J, O'donnell D, …

JBC: Channeling pain

<i>The role of resurgent currents in inherited pain syndromes</i><p>By Sapeckshita Agrawal<p>Nociceptors are nerve cells that sense potentially harmful stimuli …

Painless: a Q&A with Geoff Woods

Geoff Woods (Image copyright: Geoff Woods)<p><i>How can studying rare diseases help those with more common conditions? To mark</i> <i>Rare Disease Day</i><i>, Ellen</i> …

Changing The Channel | March 24, 2014 Issue - Vol. 92 Issue 12 | Chemical & Engineering News

<b>Burning, stabbing, sharp</b>—these are the words patients often reach for when a doctor asks them to describe their pain. Doctors have their own words …