Forensic Pathophysiology

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The evolution of oral anticoagulants

Medicine

The Diverse Biological Functions of Neutrophils, Beyond the Defense Against Infections.

2017 Feb;40(1):311-323. doi: 10.1007/s10753-016-0458-4.<p>1Transplantation Biology Research Division, State Key Laboratory of Membrane Biology, …

Biology

The pathophysiology of traumatic brain injury at a glance | Disease Models & Mechanisms

• Abramov, A. Y. and<br>• Duchen, M. R.<p>(2008). Mechanisms underlying the loss of mitochondrial membrane potential in glutamate excitotoxicity.Biochim. …

Neuroscience

Coagulation complications following trauma.

2016 Nov 22;3:35. eCollection 2016.<p>1U.S. Army Institute of Surgical Research, 3698 Chambers Pass, JBSA-Fort Sam Houston, Houston, TX 78234-6315 …

Medicine

Updated concepts on the pathophysiology and the clinical management of trauma hemorrhage and coagulopathy. - PubMed

Uncontrolled hemorrhage and subsequent trauma-induced coagulopathy (TIC) are still the principle causes for preventable death after trauma and early …

Medicine

Acute traumatic coagulopathy and trauma-induced coagulopathy: an overview

Trauma remains a leading cause of death and permanent disability in adults despite advances in systematic approaches including prevention, …

Neuroscience

Nonthrombotic pulmonary embolism.

2009 Aug;34(2):452-74. doi: 10.1183/09031936.00141708.<p>1Department of Critical Care Medicine, ZA, Antwerp University Hospital, University of Antwerp, …

Foreign Body Reaction

foreign

Exercise-Induced Emergencies in the Heat: Rhabdomyolysis & Exertional Heat Stroke - emDOCs.net - Emergency Medicine Education

<b>Authors: Michelle Y. O’Connor (@michelleyoc – Medical Student, Icahn School of Medicine at Mount Sinai) and Moira Carroll, MD (EM Resident Physician,</b> …

Prehospital immune responses and development of multiple organ dysfunction syndrome following traumatic injury: A prospective cohort study

Abstract<p>Background<p>Almost all studies that have investigated the immune response to trauma have analysed blood samples acquired post-hospital …

Signatures of inflammation and impending multiple organ dysfunction in the hyperacute phase of trauma: A prospective cohort study

Abstract<p>Background<p>Severe trauma induces a widespread response of the immune system. This “genomic storm” can lead to poor outcomes, including …

Neuroscience

Severe chest pain in an asthmatic patient

A 20 year old woman with a history of asthma presented to the emergency department complaining of shortness of breath and sharp pains in her chest …

Medicine

Sepsis

Introduction<p><b>Sepsis is a rare but serious complication of an infection.</b><p>Without quick treatment, sepsis can lead to multiple organ failure and …

Medicine

Neutrophil

The earliest morphologically distinct myeloid cell is a myeloblast. Cell with myeloid commitment at stages of differentiation between the …

Reading.php Lab

Myeloid Cells<p>Hematopoiesis<p>Pluripotent hematopoietic stem cells (HSC) in the marrow differentiate into all of the different circulating blood cells. …

Medicine

Hemolytic uremic syndrome caused by E. coli O157 infection. - PubMed

1Western Michigan University Homer Stryker M.D. School of Medicine, 300 Portage St, Kalamazoo, MI, 49007, USA.2Bronson Methodist Hospital, Kalamazoo, …

Medical Research

BBC Horizon Turned on by Danger 1997

The Danger Model: A Renewed Sense of Self

For over 50 years immunologists have based their thoughts, experiments, and clinical treatments on the idea that the immune system functions by …

Time for trauma immunology

1. Xiao W, Mindrinos MN, Seok J, Cuschieri J, Cuenca AG, Gao H, et al. A genomic storm in critically injured humans. J Exp Med. 2011 Dec 19; 208(13): …

Medicine

16 Bits of Anaphylaxis

References and Resources<p>Management of anaphylaxis infographic<p>(pdf | online)<p>Second symposium on the definition and management of anaphylaxis …

The main symptoms of acidosis #FOAMed #FRCEM #PLAB https://t.co/xZM3mnhLzG

Exercise physiology: from normal response to myocardial ischemia – ECG interpretation

Physiological principles of exercise stress testing, myocardial ischemia and ischemic symptoms<p>Understanding the basic principles of exercise …

iSepsis - Introduction to the iSepsis Website

Editors' Note<p>Paul Marik approached us for some tips on starting a sepsis website. We thought it would be great to fold the site into the EMCrit …

Trauma, Burns and Drowning

Emergency Management of Severe Trauma<p>Specific Injuries and Complications of Polytrauma<p>Techniques in Trauma Management<p>Thermal Injuries and …

Deranged Physiology |

Quick Links and Navigation<p>Quick links to Required Revision topics and SAQs<p>Infectious Disease Antibiotics and Sepsis<p>122 questions<p>Respiratory Medicine …

Takutsubo cardiomyopathy and flash pulmonary edema in a trauma patient. - PubMed

BACKGROUND:<p>First described in Japanese literature in 1991, Takotsubo cardiomyopathy (TCM), or "broken heart" syndrome, continues to be described in …

Environmental Temperature Deaths

Podcast: Play in new window | Download |<p>Subscribe: iTunes | Android | RSS | More<p>The determination of the cause of death from exposure to extreme …

Why we should all know more about sepsis