codongenomics

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Mr. Xun Xu serves as Executive Director of BGI Research and leads the technology development in the area of molecular biology, information …

Biology

Visualizing exome coverage depth - Seven Bridges

The coverage of a base pair in a sequencing run is the number of times that it was sequenced. We usually estimate coverage in an intuitive way: by …

Health Care

How I built a killer tech company outside of Silicon Valley

<i>Adam Miller is CEO of Cornerstone OnDemand.</i><p>Remember 1999? Silicon Valley was overflowing with hundreds of millions in venture capital, thousands of dot-com business plans, and foosball tables up and down the San Francisco peninsula. I was about 3,000 miles away, incubating my own startup – a …

Big data hits the big time: Datameer triples revenues in a year

Heard of the “big data” craze? If not, you’re living in a cave. Successful companies of the future, smart people say, are going to be those that quickly and ruthlessly measure and analyze all of their data.<p>And like in all big rushes, the companies providing the picks and shovels can make a …

Why predicting the phenotypic effect of mutations is hard

By now, we’re probably all familiar with Niels Bohr’s famous quote that “<i>prediction is very difficult, especially about the future</i>”. Although Bohr’s …

Why I Let My Students Cheat On Their Game Theory Exam

Teaching people game theory is good. Making them live it is even better, says UCLA professor Peter Nonacs.<p>On test day for my Behavioral Ecology class at UCLA, I walked into the classroom bearing an impossibly difficult exam. Rather than being neatly arranged in alternate rows with pen or pencil in …

SV Angel Says Health Informatics Is One Of Its New “Megatrends”

SV Angel, one of the Valley’s best-known early-stage firms, says it’s starting to look heavily at health startups that take a “software-first approach” towards human biology, medical research and patient care.<p>The firm has always had a list of six to eight “megatrends” that it invests prolifically …

How the internet is making us poor

Everyone knows the story of how robots replaced humans on the factory floor. But in the broader sweep of automation versus labor, a trend with far greater significance for the middle class—in rich countries, at any rate—has been relatively overlooked: the replacement of knowledge workers with …

Income Inequality