carlsandstrom

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Sveriges största privatekonomiblogg

Välkommen! Kul att du tittar förbi. Sedan 2007 har jag bloggat och numer även poddat om privatekonomi. Målet är att hjälpas åt med konkreta tips, råd …

Ekonomisk trygghet

40procent 20år - Utdelning & Värdeinvestering

Gustavs aktieblogg

Spartacus Invest

FINANSMAMMAN

Aktieingenjören

Infective Endocarditis - Michael Klein, Andrew Wang, 2016

Podcast 138 – Vasopressor Basics

There is a ton to speak about regarding vasopressors, but before we get to the edge cases, we need to set-up a foundation.EMCrit by Scott Weingart.

Timing of norepinephrine in septic patients: NOT too little too late

1.<p>Earlier initiation of vasopressor therapy raises the MAP to a level that facilitates tissue perfusion and prevents onset or progression of organ …

Methylglyoxal as a new biomarker in patients with septic shock: an observational clinical study

Abstract<p>Introduction<p>The role of reactive carbonyl species, such as methylglyoxal (MG), has been overlooked within the context of the sepsis syndrome. …

Biomarkers for acute kidney injury: is NGAL ready for clinical use?

In a previous issue of <i>Critical Care</i>, Matsa and colleagues [1] suggest that, in patients with no kidney disease prior to admission to the ICU, both …

Citrate for continuous renal replacement therapy: safer, better and cheaper

NephroCheck®—can we predict AKI in the ICU? And then what?

Nephrologists have been looking for sensitive biomarkers to predict AKI. Efforts have been made and the idea of “renal angina” was proposed by …

Delirium, Steroids, and Cardiac Surgery : Anesthesia & Analgesia

Brown, Charles H. IV MD, MHS*; Neufeld, Karin J. MD, MPH†; Needham, Dale M. MD, PhD‡§<p>doi: 10.1213/ANE.0000000000000412<p>Editorials: Editorial<p>From the …

Measuring pain in non-verbal critically ill patients: which pain instrument?

Abstract<p>Pain is experienced by many critically ill patients. Although the patient’s self-report represents the gold-standard measure for pain, many …

Septic acute kidney injury: molecular mechanisms and the importance of stratification and targeting therapy

Acute kidney injury (AKI) is a very common and especially formidable clinical problem in the ICU, where mortality rates approach 25% and soar to 50 …

Sleep-disordered breathing is a risk factor for delirium after cardiac surgery: a prospective cohort study

All patients (n = 92)<p>No postoperative delirium (n = 48)<p>Postoperative delirium (n = 44)<p>P<p>Male, n (%)<p>66 (60.6)<p>35 (72.9)<p>31 (70.4)<p>0.082<p>Body mass index …

Resuscitation Fluids

<b>1.</b> Lewins R. Saline injections into the veins. London Medical Gazette. April 7, 1832:257-68.<p><b>2.</b> Lee JA. Sydney Ringer (1834-1910) and Alexis Hartmann …

Cardiac arrest patients have an impaired immune response, which is not influenced by induced hypothermia

Abstract<p>Introduction<p>Induced hypothermia is increasingly applied as a therapeutic intervention in ICUs. One of the underlying mechanisms of the …

Clinical Trials

Plasma and urine neutrophil gelatinase-associated lipocalin in the diagnosis of new onset acute kidney injury in critically ill patients

Patient demographics<p>The flow chart depicting the patient enrolment is described in Figure 1. Five hundred and fifty consecutive patients were …

Measuring biomarkers of acute kidney injury during renal replacement therapy: wisdom or folly?

Abstract<p>Early data are now appearing relating to the measurement of biomarkers of acute kidney injury during renal replacement therapy. These data go …

Adrenomedullin: a vasodilator to treat sepsis?

Abstract<p>Adrenomedullin is a vasodilatory polypeptide with pleiotropic effects secreted by various organs. Adrenomedullin is produced first as a …

Inflammation biomarkers and delirium in critically ill patients: new insights?

Abstract<p>The pathophysiological mechanism of the serious and frequently occurring disorder delirium is poorly understood. Inflammation and sepsis are …

Continuous glucose control in the ICU: report of a 2013 round table meeting

Definitions<p>CGM has been proposed as a means to improve management of dysglycemia. Although termed ‘continuous’, current systems still sample …

Diabetes

Management of Atrial Fibrillation - Payman Zamani, Ralph J. Verdino, 2015

TechTool Thursday 051 FindZebra

<b>TechTool review Search Engine – FindZebra</b><p>This week’s Tech Tool focuses on a fabulous website called FindZebra. It does exactly what the title …

Computer Science

INTENSIVE • LITFL

• ‘Labs and Lytes‘: case-based problems for developing knowledge and problem-solving skills<br>• support materials for educational courses run by The Alfred …

Intensive Care

Extracorporeal life support devices and strategies for management of acute cardiorespiratory failure in adult patients: a comprehensive review

Abstract<p>Evolution of extracorporeal life support (ECLS) technology has added a new dimension to the intensive care management of acute cardiac and/or …