Meghan Brock

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UMMS scientists show proof-of-principal for silencing extra chromosome responsible for Down syndrome

Scientists at UMass Medical School are the first to establish that a naturally occurring X chromosome "off switch" can be rerouted to neutralize the …

Shutting Down the Extra Chromosome in Down’s Syndrome Cells

Many genetic disorders are caused by faulty versions of a single gene. In the last decade, scientists have made tremendous strides in correcting these faults through “gene therapy”—using viruses to sneak in working versions of the affected genes.<p>But some disorders pose greater challenges. Down’s …

Genetics

Down Syndrome Treatment Study Shows Experimental Drug Reverses Cognitive Deficits In Mice

There's still no cure for Down syndrome, but recent research is raising hopes that drugs can be found to counter the cognitive deficit that characterizes the genetic disorder.<p>In July, University of Massachusetts researchers said they had found a way to shut down the extra chromosome that causes the …

Drug Cures Mice Of Down Syndrome With A Single Dose

But it's not a cure for humans yet.<p>Cure Down syndrome with a single injection? Well, maybe--if you're a mouse. A team of scientists from John Hopkins University and the National Institutes of Health have cured newborn mice of Down syndrome by injecting them with a drug that stimulates what's called …

New Genetic Therapy Provides Breakthrough for Down Syndrome

Every year, 6,000 American babies are born with an extra copy of chromosome 21, the genetic cause of Down Syndrome. But this week, doctors at the …