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Unlocking chemistry: it's time to make the subject as open as bioscience

Now that millions of patented compounds are open information, chemistry has a chance to catch up, says Peter Murray-Rust<p>The conventional business model for chemical information has been to collect it, enhance it, then charge for access. This started with the visionary Friedrich Konrad Beilstein who …

Bad Statistics, and Bad Training, Are Sabotaging Drug Discovery

Opinion<p>Opinion<p>One of the most widely read college textbooks in the 1960s and ‘70s was How to Lie with Statisticsby Darrell Huff. Despite the humorous …

Analysts score the winners in the FDA's new 'breakthrough' category

A year after the FDA began to roll out the first of its breakthrough therapy designations, the analysts at Leerink Swann have concluded that while …

BrainStorm says stem cells helped patient with ALS and MG | Reuters

TEL AVIV (Reuters) - A patient suffering from both ALS and myasthenia gravis (MG) showed significant improvement in cognitive and motor function following treatment with BrainStorm Cell Therapeutics adult stem cells, according to a published case report.<p>Israel-based BrainStorm said on Monday a case …

Is the audience listening? FDA wants to spy on social media to find out

Do people listen to the FDA? The agency wants to know--and it's planning to track online chatter to find out. As <i>Regulatory Focus</i> reports, the agency …

30 Under 30: The Young Scientists And Entrepreneurs Discovering Our Future

<i>This post was co-authored with Andrea Navarro, a member of the Forbes wealth team who co-curated the 30 Under 30 in Science and Healthcare this year.</i><p>Researchers who have not even hit thirty yet have played key roles in some of the biggest scientific discoveries of the past few years, plumbing the …

Mediterranean Diet Protects Against Diabetes, Regardless of Weight Loss

Even if it doesn’t lead to weight loss, a Mediterranean diet could help prevent the onset of type 2 diabetes, according to a subanalysis of last year’s influential PREDIMED study. In the main trial, reported in the <i>New England Journal of Medicine</i>, nearly 7500 people at high risk for cardiovascular …

Don’t Abandon Innovation — Simplify It

My fellow HBR blogger Bill Taylor recently made a pitch for all of us to stop using the word “innovation” in 2014. Despite his plea, I suspect this word isn’t going anywhere. It’s too important as a driver of growth and renewal. What can be done, in the spirit of Bill’s admonishment, is to stop …

Why it's time for brain science to ditch the 'Venus and Mars' cliche

Reports trumpeting basic differences between male and female brains are biological determinism at its most trivial, says the science writer of the year<p>As hardy perennials go, there is little to beat that science hacks' favourite: the hard-wiring of male and female brains. For more than 30 years, I …

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Science

This headband promises to help you take control of your dreams

Andrew Smiley was sitting inside a huge, ornate dining hall when he began to notice the lights pulsing overhead. That’s weird, he thought. He stood up to get a better look, drawing the eyes of those around him. Suddenly, he knew what was happening, and what to do next: he bolted, diving through a …

Brain Cells 'Geotag' Memories To Cache What Happened — And Where

Think back to an important event in your life: a graduation, a birth, a special Thanksgiving dinner. Chances are you're remembering not only what happened, but also where it happened. And now scientists think they know why.<p>As we form so-called episodic memories, the brain appears to be using …

Mapping Emotions On The Body: Love Makes Us Warm All Over

Close your eyes and imagine the last time you fell in love. Maybe you were walking next to your sweetheart in a park or staring into each other's eyes over a latte.<p>Where did you feel the love? Perhaps you got butterflies in your stomach or your heart raced with excitement.<p>When a team of scientists …

Steve Gleason | New Orleans Saints

Steve Gleason will always be remembered for his blocked punt on the night the New Orleans Superdome reopened for the first time after Hurricane …

Neuron Protecting Gene Found

The team found that mec-17 protects the neuron by stabilising its cytoskeletal structure.<p>Image: Sashkin/Shutterstock<p>University of Queensland (UQ) …

Get Out of Your Comfort Zone: A Guide for the Terrified

No one likes to move beyond his or her comfort zone, but that’s really where the magic happens. It’s where we can grow, learn, and develop in a way that expands our horizons beyond what we thought was possible.<p>Also, it’s terrifying.<p>For me, operating beyond my comfort zone was participating in …

Who Will Create the Future?

<i>Who will offer the world more than a dead end?</i><p>Consider: Walmart is the biggest employer in America.<p>The typical Walmart “associate” (sorry—I meant Highly Exploited and Vulnerable Person With No Access to Healthcare, Job Security, Or Other Benefits, All of Which Are Subsidized By the Public Purse, …

Human Perseverance Linked to Brain Region

A person's willingness to push through hard times and overcome obstacles may come from a small network of neurons near the center of the brain, …

Humans May Have Fewer Genes Than Worms

How many protein-coding genes does a human have? Far fewer than previously thought.<p>Once upon a time in the 1960s, scientists thought the human genome might contain as many as 2 million genes, units of DNA that code for proteins. But ever since then, the estimated number has been steadily shrinking. …

Two Views Of Death: The Scientist And The Novelist

Here are two completely different ways of looking at death. One is a completely objective, coldly beautiful perspective. The other is deeply personal and troubling. Both are worth reading.<p>Here’s the scientific view:<p>Your probability of dying during a given year doubles every 8 years. For me, a …

Perspectives on VC-Backed Biotech: Looking Backward & Forward

Tis the season for reflecting and predicting, so I figured I’d follow the custom and share some of my thoughts about the state of biotech in 2013 and …

Neuralstem To Raise $19.65 Million In Registered Direct Offering

ROCKVILLE, Md., Jan. 3, 2014 /PRNewswire/ -- Neuralstem, Inc. (NYSE MKT: CUR) announced today that it has entered into agreements with leading …

Football lovers grant dying Spurs fan his final wish

A dying man’s request to watch Tottenham Hotspur one last time has been answered.<p>Glenn Phillips, 48, was diagnosed with motor neurone disease (MND) …

A step ahead of controversial transparency rules, Sanofi commits to open access

<i>Sanofi CEO Chris Viehbacher</i><p>Sanofi is starting the New Year with a resolution to join the open-access movement. But it's keeping the vaults firmly …

Intermittent fasting: The good things it did to my body

<b>Many of the changes in my body when I took part in the clinical trial of an intermittent fasting diet were no surprise. Eating very little for five days each month, I lost weight, and I felt hungry. I also felt more alert a lot of the time, though I tired easily. But there were other effects too</b> …

Diabetes

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If you’re thinking about investing money and time into settling a personal injury claim, there are lots of factors that you would have to think …

MAPT gene is associated with sporadic amyotrophic lateral sclerosis in the Chinese Han population

The Year in Plagues: The End of Antibiotics, Fist Bump for Health, and More

In case you haven't had enough end-of-year lists, here are links to my personal favorite stories from 2013. Think I missed something big? Add it in the comments.<p>Also, I got the two-set <i>Encyclopedia of Pestilence, Pandemics, and Plagues</i> for Christmas from my thoughtful husband (see photo), which I …