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This 30-Day Plank Challenge Will Transform Your Body

A strong core is the foundation of a strong body. Think about it: A tree would fall if its trunk weren't solid and stable. Doing core work isn't just …

Workouts

Why Atul Gawande Will Soon Be The Most Feared CEO In Healthcare

When news broke that Dr. Atul Gawande had been named CEO of the Amazon-Berkshire-JPMorgan Chase healthcare partnership, industry insiders were quick to raise doubts about his credentials.<p>Some pointed to his limited administrative experience, questioning how someone who has never managed a hospital …

11 Finished Book Series You Can Marathon-Read This Summer

Summer is upon us, which means we book nerds finally have time to read all those great series we have been meaning to get around to. On the list …

The Quant King, the Drug Hunter, and the Quest to Unlock New Cures

Ten years ago, drug hunter Mark Murcko was thinking about motion.<p>Then the chief technology officer of Vertex Pharmaceuticals Inc., Murcko was a …

Protein

A Biotech Executive Faces End-Stage Cancer As A Patient

For years, Michael Becker was one of the drug executives navigating swarms of cancer doctors at the annual meeting of American Society of Clinical Oncology, where 40,000 people gather every year to talk about the hottest cancer-killing drugs. This year he came back, but it was very different. This …

Bill And Melinda Gates Start A Nonprofit Biotech In Boston

Over the past year or so, the Bill and Melinda Gates Foundation has built what is essentially a nonprofit biotechnology company in Boston, with a $100 million budget and a staff targeted to grow to as many as 100 people.<p>“What keeps me awake is we have all this capital, we have all this opportunity …

More Thoughts on AbbVie’s Rova-T Implosion

I wrote a couple of months ago about the disappointing results that AbbVie had obtained with their cancer stem cell therapy “Rova-T” (rovalpituzumab …

New Immunotherapy Treatment Removes All Tumors In Woman With Advanced Metastatic Breast Cancer

Research published today in <i>Nature Medicine</i> by scientists at the National Cancer Institute (NCI) has described a new immunotherapy approach, which led to a complete disappearance of tumors in a woman with advanced metastatic breast cancer who only had months to live.<p>The findings show how …

Cancer

The 18 Best Barbecue Recipes Ever

Before you fire up the grill this weekend, remember: This barbecue could be your last of the season. Carpe diem, people—try one of these 18 …

Cooking

The 19 coolest places for a European holiday in 2018, according to travel experts

Globetrotters are always looking for inspired travel recommendations from those in the know in order to experience new destinations in the most authentic way possible — and those passed by word-of-mouth are always best.<p>As summer kicks off, Business Insider asked friends, colleagues, and some of the …

European Travel

NBA coach Steve Kerr says the NFL's anthem decision is what's wrong with our country right now https://t.co/IkHB2LdIc0

Bill Gates Shares the 5 Books You Should Read This Summer

Bill Gates wants you to do some serious thinking this summer. For his annual list of the best books to read this season, Gates has selected five …

FDA Approves Amgen's Migraine Drug

The U.S. Food and Drug Administration has approved Amgen’s erenumab (which it’s calling Aimovig) to prevent migraines.<p>“We feel pretty strongly this is a huge opportunity to help patients with a targeted, migraine specific medication that’s broadly efficacious, and can be administered in a …

Amgen’s new migraine drug will cost 30 percent less than Wall Street expected

Amgen will charge $6,900 a year for a new drug that can spare migraine sufferers a few headaches each month, a price that comes in well below Wall …

Matching therapeutic modality and molecular mechanism

[<i>Disclaimer: I am an employee of Celgene. The views reported here are my own.</i>]On a recent family vacation to Cumberland Island, a 9,800-acre barrier …

Bristol-Myers Squibb drops phase 3 trials of $800M IDO drug

Bristol-Myers Squibb has pulled two phase 3 clinical trials of the IDO1 inhibitor it acquired through an $800 million takeover of Flexus. The studies …

Incyte wipes out late-phase epacadostat program after pivotal failure of Keytruda combination

Incyte has taken an ax to its suite of late-phase epacadostat trials after digesting the implications of last month’s pivotal study blowup. The cull …

‘A full rescue’: Drug injected before birth treats rare genetic disorder

As soon as she saw her baby, Sarah Yaroch knew. Her father had the disorder, as did her nephew, and now she could see the telltale signs in her own …

Pregnancy

Can Takeda actually close its $65B deal to buy Shire? Maybe, but analysts aren't sure they should

Takeda has upped its offer to buy Shire $SHPG for a mix of stock and cash worth close to $65 billion, which is good enough for the Lexington, …

Investing

How Blueprint Medicines Got The Blues

Last Sunday, lots of people were gushing about Blueprint Medicines’ experimental cancer drug. So why has the company’s share price dropped 20%?<p>The answer: biotech fund managers are paying attention to a scientist who poked holes in Blueprint’s data on-stage at the annual meeting of the American …

A cancer drug tailored to your tumor? Experts trade barbs over ‘precision oncology’

For people with advanced cancer who are running out of options, many cancer centers now offer this hope: Have your tumor’s genome sequenced, and …

Cancer

The Best Pastries in Paris, According to Top Chefs

It’s been the world’s favorite destination for luscious baked goods since forever. Now the French capital is outperforming even itself.<p>By Kate …

Inventor, chemist, and CRISPR craftsman: Inside David Liu’s evolution workshop

David R. Liu is an inventor on a winning streak. As a young chemist, he quickly mastered techniques for studying life’s most complex molecules and …

A 32-Year-Old's Startup, Inspired By A Health Scare, Sells For $275 Million

Surbhi Sarna was 13 and working on a school assignment in her bedroom when she felt a pain in her side so severe she blacked out. It was a complex ovarian cyst, doctors told her. What they couldn’t tell her at first: whether or not it was cancer. (It wasn’t.)<p>A quest to detect ovarian cancer for …

17 Books About Female Scientists That Will Take You On Adventures Through Nature, Time, And Space

Without a doubt, femalescientists have had enormous impact on our understanding of the world and beyond. Yet, throughout the centuries much of their …

A ‘New’ J.R.R. Tolkien Book Coming This Year

Though he passed away 45 years ago, the world is luckily not in any shortage of works by J.R.R. Tolkien. Just last week we told you details about …

Literature

Strange Dog Joins Couple On Hike — Then They See What's Written On His Collar

"Hi, I'm Smokey."<p>As Scott Brown and his wife were preparing to embark on a snowy trek to a popular waterfall in Washington state this week, they …

Here are the 2018 Hugo Award nominees

The best science fiction and fantasy of 2017<p>The nominees for the 2018 Hugo Awards were announced today, representing the best science fiction and fantasy literature published in 2017.<p>The Hugo Awards are one of speculative fiction’s most prestigious prizes. Named for <i>Amazing Stories</i> editor Hugo …

Australian scientists move closer to world-beating quantum computer

Australian scientists, led by Australian of the year Michelle Simmons, have made a significant step in creating a world-beating, single-atom quantum computer.<p>Simmons and her Australian team announced on Wednesday they had built quantum bits, known as qubits, from single phosphorus atoms in silicon, …

Quantum Computing