PLOS Pathogens Pearls

7 Magazines | 599 Articles | 586 Followers | @PLOSPearls | PLOS Pathogens presents an Open Access compendium of "lessons-that-last." This living collection of short, educational, and highly useful articles addresses topics of relevance and importance within the wide-ranging field of pathogens research, with insights for trainees and scientists at all career stages. The collection is also found here:

Giant Chloroviruses: Five Easy Questions

by James L. Van Etten, David D. Dunigan


The Buzz about Honey Bee Viruses

by Laura M. Brutscher, Alexander J. McMenamin, Michelle L. Flenniken

Nudix Effectors: A Common Weapon in the Arsenal of Plant Pathogens

1. McLennan AG (2006) The Nudix hydrolase superfamily. Cell Mol Life Sci 63: 123–143. pmid:16378245<p>2. Akiyama M, Maki H, Sekiguchi M, Horiuchi T …


Expanding Host Range and Cross-Species Infection of Hepatitis E Virus

by Xiang-Jin Meng


Conquering Neutrophils

1. Bardoel BW, Kenny EF, Sollberger G, Zychlinsky A. The Balancing Act of Neutrophils. Cell Host Microbe. 2014;15(5):526–36. doi: …


Major Sensing Proteins in Pathogenic Fungi: The Hybrid Histidine Kinase Family

1. Mizuno T, Wurtzel ET, Inouye M. Osmoregulation of gene expression. II. DNA sequence of the <i>envZ</i> gene of the <i>ompB</i> operon of <i>Escherichia coli</i> and …


The Legacy of Past Pandemics: Common Human Mutations That Protect against Infectious Disease

1. Allison AC. Protection afforded by sickle-cell trait against subtertian malareal infection. Br Med J. 1954;1(4857):290–4. Epub 1954/02/06. …


Untangling the Diverse and Redundant Mechanisms of Staphylococcus aureus Biofilm Formation

by Marta Zapotoczna, Eoghan O’Neill, James P. O'Gara


A Sweet Response to a Sour Situation: The Role of Soluble Pattern Recognition Receptors in the Innate Immune Response to Invasive Aspergillus fumigatus Infections

1. Schelenz S, Barnes RA, Barton RC, Cleverley JR, Lucas SB, et al. (2015) British Society for Medical Mycology best practice recommendations for the …


Sporothrix Species Causing Outbreaks in Animals and Humans Driven by Animal–Animal Transmission

1. Schenck BR. On refractory subcutaneous abscesses caused by a fungus possibly related to the <i>Sporotricha</i>. Bull Johns Hopkins Hosp. 1898;9:286–90.<p>2. …

Commensal–Pathogen Interactions along the Human Nasal Passages

1. Casadevall A, Pirofski LA. What is a host? Incorporating the microbiota into the damage-response framework. Infect Immun. 2015;83(1):2–7. doi: …

Escaping Host Immunity: New Tricks for Plant Pathogens

1. Dangl JL, Horvath DM, Staskawicz BJ (2013) Pivoting the plant immune system from dissection to deployment. Science 341: 746–751. doi: …

Lessons from Nature: Understanding Immunity to HCV to Guide Vaccine Design

1. Mohd Hanafiah K, Groeger J, Flaxman AD, Wiersma ST. Global epidemiology of hepatitis C virus infection: new estimates of age-specific antibody to …

Dissecting Virus Infectious Cycles by Cryo-Electron Microscopy

by Kelly K. Lee, Long Gui


IL-26: An Emerging Proinflammatory Member of the IL-10 Cytokine Family with Multifaceted Actions in Antiviral, Antimicrobial, and Autoimmune Responses

by Emmanuel Stephen-Victor, Helmut Fickenscher, Jagadeesh Bayry


The Janus-Face of Bacteriophages across Human Body Habitats

by Adam Wahida, Klaus Ritter, Hans-Peter Horz


Impact of the DNA Damage Response on Human Papillomavirus Chromatin

by Dipendra Gautam, Cary A. Moody


Immune Sensing of Lipopolysaccharide in Plants and Animals: Same but Different

1. Zipfel C, Felix G. Plants and animals: a different taste for microbes? Curr Opin Plant Biol. 2005;8(4):353–60. Epub 2005/06/01. doi: …

Anti-infective Surface Coatings: Design and Therapeutic Promise against Device-Associated Infections

1. Klevens RM, Edwards JR, Richards CL, Horan TC, Gaynes RP, et al. (2007) Estimating Health Care-Associated Infections and Deaths in U.S. Hospitals, …

Location, Location, Location: Five Facts about Tissue Tropism and Pathogenesis

1. Global Burden of Disease Study C. Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic …

Immunizing against Anogenital Cancer: HPV Vaccines

by Cloe S. Pogoda, Richard B. S. Roden, Robert L. Garcea


Dumpster Diving in the Gut: Bacterial Microcompartments as Part of a Host-Associated Lifestyle

by Christopher M. Jakobson, Danielle Tullman-Ercek


Thermal Restriction as an Antimicrobial Function of Fever

by Arturo Casadevall


Estradiol Enhances CD4+ T-Cell Anti-Viral Immunity by Priming Vaginal DCs to Induce Th17 Responses via an IL-1-Dependent Pathway

by Varun C. Anipindi, Puja Bagri, Kristy Roth, Sara E. Dizzell, Philip V. Nguyen, Christopher R. Shaler, Derek K. Chu, Rodrigo Jiménez-Saiz, Hong …


Innate Resistance and Susceptibility to Norovirus Infection

by Johan Nordgren, Sumit Sharma, Anita Kambhampati, Ben Lopman, Lennart Svensson


Correlates of Protection against Norovirus Infection and Disease—Where Are We Now, Where Do We Go?

by Sasirekha Ramani, Mary K. Estes, Robert L. Atmar


Filamentous Fungi in Respiratory Infections. What Lies Beyond Aspergillosis and Mucormycosis?

by Anuradha Chowdhary, Kshitij Agarwal, Jacques F. Meis


Trypanosome Mitochondrial Translation and Tetracycline: No Sweat about Tet

by Hassan Hashimi, Sabine Kaltenbrunner, Alena Zíková, Julius Lukeš


Tick–Host–Pathogen Interactions: Conflict and Cooperation

by José de la Fuente, Margarita Villar, Alejandro Cabezas-Cruz, Agustín Estrada-Peña, Nieves Ayllón, Pilar Alberdi

In Vivo Transcriptional Profiling of Human Pathogenic Fungi during Infection: Reflecting the Real Life?

by Stefanie Allert, Sascha Brunke, Bernhard Hube