PLOS Pathogens Pearls

7 Magazines | 574 Articles | 574 Followers | @PLOSPearls | PLOS Pathogens presents an Open Access compendium of "lessons-that-last." This living collection of short, educational, and highly useful articles addresses topics of relevance and importance within the wide-ranging field of pathogens research, with insights for trainees and scientists at all career stages. The collection is also found here: http://collections.plos.org/s/pearls

Innate Resistance and Susceptibility to Norovirus Infection

by Johan Nordgren, Sumit Sharma, Anita Kambhampati, Ben Lopman, Lennart Svensson

Norovirus

Correlates of Protection against Norovirus Infection and Disease—Where Are We Now, Where Do We Go?

by Sasirekha Ramani, Mary K. Estes, Robert L. Atmar

Norovirus

Filamentous Fungi in Respiratory Infections. What Lies Beyond Aspergillosis and Mucormycosis?

by Anuradha Chowdhary, Kshitij Agarwal, Jacques F. Meis

Fungi

Trypanosome Mitochondrial Translation and Tetracycline: No Sweat about Tet

1. Moullan N, Mouchiroud L, Wang X, Ryu D, Williams EG, et al. (2015) Tetracyclines disturb mitochondrial function across eukaryotic models: A call …

Translation

Tick–Host–Pathogen Interactions: Conflict and Cooperation

1. de la Fuente J, Estrada-Peña A, Venzal JM, Kocan KM, Sonenshine DE. Overview: Ticks as vectors of pathogens that cause disease in humans and …

Science

In Vivo Transcriptional Profiling of Human Pathogenic Fungi during Infection: Reflecting the Real Life?

by Stefanie Allert, Sascha Brunke, Bernhard Hube

Biology

Modulation of Host Angiogenesis as a Microbial Survival Strategy and Therapeutic Target

1. Carmeliet P, Jain RK. Molecular mechanisms and clinical applications of angiogenesis. Nature 2011;473: 298–307. doi: 10.1038/nature10144. …

Science

Virus–Host Interactions and the ARTD/PARP Family of Enzymes

1. Vyas S, Chang P. New PARP targets for cancer therapy. Nat Rev Cancer. 2014;14: 502–509. doi: 10.1038/nrc3748. pmid:24898058<p>2. Gibson BA, Kraus WL. …

Biology

Fusarium: Molecular Diversity and Intrinsic Drug Resistance

by Abdullah M. S. Al-Hatmi, Jacques F. Meis, G. Sybren de Hoog

Fungi

Viruses Utilize Cellular Cues in Distinct Combination to Undergo Systematic Priming and Uncoating

by Madhu Sudhan Ravindran, Billy Tsai

Science

Cooperation and Conflict in the Plant Immune System

1. Sinapidou E, Williams K, Nott L, Bahkt S, Tor M, et al. (2004) Two TIR:NB:LRR genes are required to specify resistance to <i>Peronospora parasitica</i> …

Botany

The Herpes Simplex Virus Neurovirulence Factor γ34.5: Revealing Virus–Host Interactions

by Douglas R. Wilcox, Richard Longnecker

Science

The Ins and Outs of Rust Haustoria

1. Mendgen K, Struck C, Voegele RT, Hahn M (2000) Biotrophy and rust haustoria. Physiol Mol Plant Pathol 56: 141–145.<p>2. Voegele RT, Struck C, Hahn M, …

Dimorphism in Fungal Pathogens of Mammals, Plants, and Insects

1. Bohse ML, Woods JP (2007) RNA interference-mediated silencing of the <i>YPS3</i> gene of <i>Histoplasma capsulatum</i> reveals virulence defects. Infect Immun 75: …

Disease to Dirt: The Biology of Microbial Amyloids

1. Fowler DM, Koulov AV, Balch WE, Kelly JW (2007) Functional amyloid–from bacteria to humans. Trends Biochem Sci 32: 217–224. doi: …

Hell's BELs: Bacterial E3 Ligases That Exploit the Eukaryotic Ubiquitin Machinery

1. Behrends C, Harper JW (2011) Constructing and decoding unconventional ubiquitin chains. Nat Struct Mol Biol 18: 520–528. doi: 10.1038/nsmb.2066<p>2. …

The Role of Horizontal Gene Transfer in the Evolution of the Oomycetes

by Fiona Savory, Guy Leonard, Thomas A. Richards

Evolution

Human and Plant Fungal Pathogens: The Role of Secondary Metabolites

1. Brakhage AA (2013) Regulation of fungal secondary metabolism. Nat Rev Microbiol 11: 21–32. doi: 10.1038/nrmicro2916<p>2. McDonagh A, Fedorova ND, …

Advances and Challenges in Computational Prediction of Effectors from Plant Pathogenic Fungi

by Jana Sperschneider, Peter N. Dodds, Donald M. Gardiner, John M. Manners, Karam B. Singh, Jennifer M. Taylor

Botany

Innate Sensing of Chitin and Chitosan

1. Merzendorfer H (2011) The cellular basis of chitin synthesis in fungi and insects: Common principles and differences. Eur J Cell Biol 90: 759–769. …

Worse Comes to Worst: Bananas and Panama Disease—When Plant and Pathogen Clones Meet

by Nadia Ordonez, Michael F. Seidl, Cees Waalwijk, André Drenth, Andrzej Kilian, Bart P. H. J. Thomma, Randy C. Ploetz, Gert H. J. Kema

Botany

Beg, Borrow and Steal: Three Aspects of Horizontal Gene Transfer in the Protozoan Parasite, Cryptosporidium parvum

1. Tyzzer EE. A sporozoan found in the peptic glands of the common mouse. Exp Biol Med. 1907;5:12–3. doi: 10.3181/00379727-5-5<p>2. Tzipori S, Widmer G. …

Emerging Paramyxoviruses: Receptor Tropism and Zoonotic Potential

by Antra Zeltina, Thomas A. Bowden, Benhur Lee

Science

The Diverse Role of NK Cells in Immunity to Toxoplasma gondii Infection

by Jason P. Gigley

Science

Go Forth and Colonize: Dispersal from Clinically Important Microbial Biofilms

1. Monds RD, O'Toole GA (2009) The developmental model of microbial biofilms: ten years of a paradigm up for review. Trends Microbiol 17: 73–87. doi: …

Science

SeXX Matters in Infectious Disease Pathogenesis

1. Klein SL, Pekosz A, Passaretti C, Anker M, Olukoya P. Sex, gender and influenza. Geneva: World Health Organization, 2010 July.<p>2. Klein SL, Roberts …

The March towards a Vaccine for Congenital CMV: Rationale and Models

by Kristy M. Bialas, Sallie R. Permar

Science

When the Fight against Fungi Goes Wrong

1. Brown GD, Denning DW, Levitz SM (2012) Tackling human fungal infections. Science 336: 647. doi: 10.1126/science.1222236. pmid:22582229<p>2. Puel A, …

A Mother’s Gift: Congenital Transmission of Trypanosoma and Leishmania Species

by Tara Grinnage-Pulley, Benjamin Scott, Christine A. Petersen

Science

The Link between Plasmodium falciparum Malaria and Endemic Burkitt’s Lymphoma—New Insight into a 50-Year-Old Enigma

by David Thorley-Lawson, Kirk W. Deitsch, Karen A. Duca, Charles Torgbor

Science