Novartis Science

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Scientists Create a Window into the Brain

Lipids in the brain, often concentrated in cell membranes, block light from reaching the intricate structures that comprise the organ, which is the …

The Brain

CRISPR deployed to combat sickle-cell anaemia

Studies in mice highlight the promises — and challenges — of CRISPR–Cas9 gene editing.<p>A mutation in a single DNA letter causes a painful and …

Scientists turned mouse skin cells into egg cells — and made babies

Scientists have successfully turned skin cells into egg cells and used them to create viable offspring without the use of actual eggs for the first time. Just a small percentage of the mouse cells created in the lab led to live births, researchers reported Monday in Nature, but the healthy pups …

Genetics

This plant grows shimmering blue leaves to help it survive in the dark

Imagine a place where the oceans were full of purple algae and plants on the forest floor glowed a gorgeous, iridescent blue.<p>This is not the setting of a Dr. Seuss story or a science fiction novel. This place is Earth.<p>It may be an article of faith that plant life on our planet must be verdant: …

Science Fiction

Cameras monitor hospital patients’ vital signs from afar

Trials at John Radcliffe and Broadmoor hospitals show how special software can monitor patients' breathing and heart rate from camera images

Health

Scientists Say They've Identified the Physical Source of Depression in the Brain

Depression isn't just 'all in your head'.<p>The region of the brain that serves as the physical source of feelings of depression has been identified, …

A New Tack to Stave Off Alzheimer's Years before the First Symptom

The new mantra for researchers fighting Alzheimer’s disease is “go early,” before memory loss or other pathology appears. The rationale for this …

Dementia

Robotic Mussels Track Rising Temperatures for Climate Research

If you were to stare down into one of a few dozen intertidal pools at low tide, as waves glide in and out, you might have a hard time spotting the robots.<p>That’s because they look just like the real mussels that surround them. (If you want to see how hard it is, try clicking on the robotic mussel in …

Stopping free radicals at their source | Novartis Institutes for BioMedical Research

Free radicals stand accused of aiding or abetting just about every form of human disease. These chemically reactive molecules, flooding through cells …

Vitamins

Novel study of pancreatic cancer aims to give patients more treatment options

Just 3 percent of adult cancer patients participate in clinical trials of experimental treatments. In a novel effort to boost that number, a national …

Cancer

Scientists Have Figured Out How to Help Nerve Fibres Repair Themselves

A whole new way to treat paralysis.<p>Scientists have figured out how to make nerve fibres repair themselves in mice, having identified a gene that …

Biologists plan scoring system for antibodies

Manufacturers and users will rank reagents to improve the reliability of research.<p>Biomedical experts plan to create a scoring system that will help …

Biology

Stepping toward regenerative medicine for diabetes | Novartis Institutes for BioMedical Research

“Son, you need to live fast and loose because you’re not going to live very long,” the doctor told ten-year-old Chris Stiehl. It was 1961 and Stiehl …

Massive U.K. Brain-Mapping Project Releases First Results

Last week researchers released the first results from the UK Biobank Imaging Study, a massive effort that ultimately aims to scan the brains of …

The Brain

Genomic analysis allows researchers to identify three subtypes of prostate cancer

Many men with prostate cancer have slow-growing tumors that don’t require aggressive treatments such as surgery or radiation therapy, whereas others …

Cancer

Robot surgeons and artificial life: the promise of tiny machines

<b>The 2016 Nobel Prize in chemistry has been awarded for the design and synthesis of the world's smallest machines. The work has overtones of science fiction, but holds huge promise in fields as diverse as medicine, materials and energy.</b><p>All grand endeavours start small.<p>This is especially true of …

Robotics

In a medical first, brain implant allows paralyzed man to feel again

For the first time, scientists have helped a paralyzed man experience the sense of touch in his mind-controlled robotic arm.<p>For the cutting-edge experiment, a collaboration between the University of Pittsburgh and the University of Pittsburgh Medical Center, electrodes smaller than a grain of sand …

The Brain

Stopping Alzheimer’s disease before it starts | Novartis Institutes for BioMedical Research

Jamie Tyrone got her first look at Alzheimer’s disease at the age of 10, in the mid-1970s, during a visit with her great-grandmother. “She was …

A cellular drama at the heart of a researcher’s family

Early in her research career, Jennifer Allport-Anderson lived human dramas on two vastly different scales. One was at home, with her husband and …

Health

The Breast Has Its Own Microbiome--and the Mix of Bacteria Could Prevent or Encourage Cancer

The gut microbiome has stolen the show when it comes to the recent explosion of research on the bacteria that thrive within us. But bacteria also …

Cancer

Scientists Just Developed a Video That Induces the Same Visual Hallucinations in Healthy People

Do you see the grey blobs?<p>Researchers have discovered a way to consistently induce the same visual hallucination in healthy people - without …

Cells grown from skin could provide radical new treatment for heart attacks

Stem cell therapy creates heart cells capable of partially repairing damage to the organ, although more work needed before human trials can take place<p>Scientists have taken a step towards a radical new treatment for heart attacks with a stem cell therapy that can partially repair damage to the organ.<p>…

Watch sea urchins turn themselves inside out to be reborn

Every summer, millions of people head to the coast to soak up the sun and play in the waves. But they aren’t alone. Just beyond the crashing surf, …

This Portable Vaccine Kit Just Needs Added Water

Brilliant.<p>Even when the right drugs are available, they can't always get to the people who need them the most - but this new portable vaccine kit …

Viruses

Watch antibiotic-resistant bacteria evolve right before your eyes

<i>A time-lapsed video of E. coli bacteria developing resistance to increasingly higher doses of antibiotics over 10 days. Video courtesy: Kishony</i> …

Bacteria

5 things you need to know about antimicrobial resistance

<b>(CNN) —</b> Global leaders met at the United Nationals General Assembly in New York Wednesday to address what experts are calling one of the biggest threats to global health: antimicrobial resistance.<p>It is only the fourth time in UN history that a health issue has been discussed at the assembly, after …

Health

Harnessing the amazing work of the 40 trillion chemists in your gut microbiome

First Opinion<p>Deep in your gut, 40 trillion chemists are hard at work helping you digest your lunch, making essential vitamins and nutrients you can’t …

Biology

Concussion researchers spark hope with new method

In the Lab<p>Concussion researchers spark hope with a new tool to diagnose brain damage<p>The diagnosis begins with the brain being pulled out of the skull.<p>…

Dementia

Synthetic blood vessel breakthrough could transform children's heart surgery

Children born with serious heart defects could be treated in a single operation as researchers create artificial blood vessels that grow normally with age<p>A breakthrough in the manufacture of synthetic blood vessels has raised hopes that children born with serious heart defects could be treated in a …

New "Artificial Synapse" Gets Closer to Mimicking Brain Connections

A brain-inspired computing component provides the most faithful emulation yet of connections among neurons in the human brain, researchers say.<p>The …

The Brain