Mimicry Huang

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Antibacterial drug discovery in the resistance era.

Related Articles<b>Antibacterial drug discovery in the resistance era.</b>Nature. 2016 Jan 21;529(7586):336-43Authors: Brown ED, Wright GDAbstract<br>The …

Microbiology

Why is antibiotic resistance a deadly emerging disease?

2016 May;22(5):405-7. doi: 10.1016/j.cmi.2016.01.012. Epub 2016 Jan 22.<p>1Unité des Agents Antibactériens, Institut Pasteur, Paris, France. Electronic …

Biology

Combinations of mutations in envZ, ftsI, mrdA, acrB and acrR can cause high-level carbapenem resistance in Escherichia coli.

Related Articles<b>Combinations of mutations in envZ, ftsI, mrdA, acrB and acrR can cause high-level carbapenem resistance in Escherichia coli.</b>J …

Biology

Scientists disable infectious bacteria by removing key protein

Scientists have made an exciting discovery that could provide a new way to prevent bacterial infections in both humans and plants without triggering …

Microbiology

New antibacterial gel could revolutionize treatment of superbug infections

In an exclusive guest article for <i>Medical News Today</i>, Dr. Garry Laverty, PhD, from the School of Pharmacy at Queen's University Belfast in Ireland, …

How antibiotic resistance emerges

<b>This info-graphic and short description explains how antibiotic resistance arises and spreads in populations.</b><p>Laura JV Piddock1 and Victoria …

Medicine

Vaccines vs superbugs: A new weapon to fight antibiotic resistance?

The outbreak of the Zika virus, like Ebola before it, has highlighted the risk that infectious diseases can pose to the health of entire countries – …

Losing the fight against antibiotic resistance

Tackling antibiotic resistance on only one front is a waste of time because resistant genes are freely crossing environmental, agricultural and …

Genes

More MCR-1 findings lead to calls to ban ag use of colistin

The recently identified MCR-1 resistance gene that disables the last-line antibiotic colistin has further spread beyond China to distant regions, …

Public Health

Carbapenem resistance: overview of the problem and future perspectives. - PubMed

Carbapenem resistance, mainly among Gram-negative pathogens, is an ongoing public-health problem of global dimensions. This type of antimicrobial …

PubMed

看圖才能說故事!做簡報必備 10 個資訊圖表圖示資源

Easel.ly 讓任何人都能在簡報中用資訊圖表說故事

一張精彩且可以被大量傳播的資訊圖表或許需要嚴謹的數據、專業的設計,以及創造性的靈感才能製作出來,不是用什麼工具製作的問題,而是如何創作的巧妙。但是,今天這篇文章我們不是要談論這種資訊圖表。<p>還有另外一種資訊圖表不一定是宣傳或內容的核心,而只是要讓我們在解說時增加一些小小亮點,或是讓說明可以更清楚而已, …

As Antibiotic Resistance Spreads, WHO Plans Strategy To Fight It

The world is losing some of the most powerful tools in modern medicine. Antibiotics are becoming less and less effective at fighting infections. The problem has gotten so bad that some doctors are starting to ponder a "post-antibiotic world."<p>Common infections that have been easily treatable for …

Public Health

Targets for Combating the Evolution of Acquired Antibiotic Resistance.

2015 Jun 16;54(23):3573-82. doi: 10.1021/acs.biochem.5b00109. Epub 2015 Jun 5.<p>Abstract<p>Bacteria possess a remarkable ability to rapidly adapt and …

Biology

Evolution of the resistance to antibiotics of bacteria involved in urinary tract infections: a 7-year surveillance study. - PubMed

BACKGROUND:<p>We conducted a retrospective analysis on the identification and antibiogram of all bacteria isolated from urine samples with …

Medicine

補足 Gmail 回條功能: MailTrack 免費無限已讀追蹤

Outlook 中大家最喜歡使用的功能之一叫做「傳送回條」,那麼在很多人使用的 Gmail 中到底有沒有類似功能呢?其實有,在 Gmail 的 Google Apps 企業版、教育版、政府版中都有這個「<b>讀取回條</b>」功能可以開啟,只是在個人版 Gmail 中還缺少這樣的已讀回應功能。<p>所以在我之前《這些G …

Congress and the FDA - Show us the Money!

Well – the US Congress is at it again. It seems like they will do almost anything except spend money where its needed. There is a very comprehensive …

Pulling Farm Antibiotics Won't Fix All Our Superbug Woes

Earlier this week, Tyson, killer of about 2 billion chickens every year, announced that it would be phasing out the use of human antibiotics in that …

Most countries woefully unprepared to fight resistant superbugs -WHO

Superbug infections kill hundreds of thousands of people a year, and the trend is growing<p>* Resistance to antibiotics and antivirals on the rise<p>* …

Public Health

Growing Antibiotic Shortages Threaten Patient Care

A disturbing new report shows that shortages of many important antibiotics have been worsening since 2007. Antibiotics accounted for 15% of all drug shortages from 2001-13, affecting 148 anti-infectives.<p>Of particular concern, as study author Larissa May, MD, of George Washington University notes, …

Medicine

Finding new life for first-line antibiotics

Researchers have identified a single, simple measure -- recovery time -- to guide antibiotic dosing that could bring an entire arsenal of first-line …

Microbiology

Antimicrobial-Induced DNA Damage and Genomic Instability in Microbial Pathogens

1. Andersson DI, Hughes D (2014) Microbiological effects of sublethal levels of antibiotics. Nature reviews Microbiology 12: 465–478. pmid:24861036<p>2. …

Small talk with big potential: Bacterial conversation counteracts antibiotic damage

A research team led by Karina Xavier at the Instituto Gulbenkian de Ciência (IGC, Portugal) has shown that bacteria living in the intestine both talk …

Tigecycline susceptibility and the role of efflux pumps in tigecycline resistance in KPC-producing Klebsiella pneumoniae.

2015 Mar 3;10(3):e0119064. doi: 10.1371/journal.pone.0119064. eCollection 2015.<p>He F1, Fu Y1, Chen Q1, Ruan Z1, Hua X1, Zhou H2, Yu Y1.<p>1Department of …

Mutations

The role of RND efflux pump and global regulators in tigecycline resistance in clinical Acinetobacter baumannii isolates. - PubMed

AIM:<p>To analyze the expression and regulation of resistance-nodulation-division (RND) efflux systems in clinical tigecycline-nonsusceptible (TNS) …

Mutations

IDSA: National action plan for combating antibiotic resistant bacteria (carb) - a welcome effort in tackling resistance public health crisis

The Infectious Diseases Society of America (IDSA) welcomes the release of the National Action Plan for Combating Antibiotic Resistant Bacteria …

Who Is Responsible For Antibiotic Resistance?

We commonly blame physicians for overprescribing antibiotics, patients for demanding them and, increasingly, agribusiness for squandering antibiotics as growth promoters. All of those are major problems. One less-often mentioned factor is a side effect of the manufacturing process itself, where …

Microbiology

Superbug Scare At UCLA -- It's Not The Scopes That Should Scare You

There’s a big brouhaha over a cluster of infections following endoscopy at UCLA, but this needs to be placed in some perspective. It’s not the endoscopes that should scare you; it is the rise of “superbugs,” very resistant to antibiotics.<p>The procedure being scrutinized at UCLA is endoscopic …

Microbiology

UCLA Superbugs Reveal Stubborn Resistance Problem

Guest Post by Maryn McKenna<p>The UCLA Health System announced earlier this week that seven patients—two of whom died—became infected by highly drug-resistant bacteria that remained on pieces of medical equipment after disinfection, and 179 more were exposed to the bacteria and are at risk of …

Microbiology