Cold Spring Harbor Laboratory

2 Magazines | 104 Articles | 6 Followers | @CSHL | Cold Spring Harbor Laboratory (CSHL) is a private, not-for-profit research and education institution at the forefront of molecular biology and genetics.

Understanding How Zinc Affects How We Think

Poking out from many neurons in the brains are NMDA receptors, whose faulty operation has been implicated in disorders including Alzheimer’s, …

The Brain

Our Genome’s Guardian Can Break Bad

A protein known as p53 has long held the grand title of “guardian of the genome” for the protection it provides against cancer-causing mutations. New …

Nutrition

For Alan Alda, Science Communication is a State of Mind

Alan Alda, famous for his role in the classic TV series “M*A*S*H” and the PBS series “Scientific American Frontiers,” recently received a 2016 CSHL …

Science

Alan Alda and Roy Vagelos honored at 11th Double Helix Medals Dinner

Alan Alda, known as Hawkeye from the classic TV series <i>M*A*S*H</i> and host of PBS’s <i>Scientific American Frontiers</i>, and Roy Vagelos, retired chairman and …

Natural History

More people will say “I used to have cancer”

That’s a major goal for Dr. David Tuveson, the new director of CSHL’s Cancer Center. After seeing too many patients with dismal options as a cancer …

The Brain Atlas (Base Pairs Episode 7)

<i>One in six people suffers from a mental disorder, and yet, compared to cancer and infectious disease, neuropsychiatric treatment options have barely</i> …

Science

For Alan Alda, science communication is a state of mind

<i>Alan Alda, famous for his role in the classic TV series “M*A*S*H” and the PBS series “Scientific American Frontiers,” recently received a 2016 CSHL</i> …

Get busy or get RNAi

All cells are either busy reproducing or “quiescently” waiting to reproduce. The latter category includes many critical cells in our bodies, like …

Emma’s Story: with science on her side, one little girl finds hope

Emma’s prognosis was grim. Spinal Muscular Atrophy (SMA) was crippling her and it seemed that nothing could stop it. That’s now changing thanks to an …

No (real) moustache required to join the “Movember” party

Prostate cancer is the most common non-skin cancer among American men, but most of the prostate cancer researchers at CSHL have zero risk of …

Cancer can hijack our web-slinging immune cells

Immune cells called neutrophils have an amazing weapon: they can shoot out webs of DNA to capture invaders. But if neutrophils are Spider-Man, cancer …

The case for investing in young scientists

When he was just 27 years old, Adrian Krainer was offered the opportunity to run his own lab at CSHL. Research by his team has led to the development …

No (real) moustache required to join the “Movember” party

<i>Prostate cancer is the most common non-skin cancer among American men, but most of the prostate cancer researchers at CSHL have zero risk of</i> …

When Antioxidants are Pro-cancer (Base Pairs Episode 6)

<i>Recent research on antioxidant levels in the cells of pancreatic cancer patients is homing in on a new, safer avenue for treatment. And it’s not what</i> …

HIV/AIDS Research – Its History and Future

“I wanted to bring together scientists who fought the HIV/AIDS epidemic for 35 years to share their accomplishments and discuss the future of the …

The Claire Friedlander Family Foundation Donates $200,000 for New...

The Claire Friedlander Family Foundation Donates $200,000 for New Sequencer<p>CSHL Association Director Peter J. Klein is President of the Claire …

A theoretical physicist’s approach to breast cancer

Ideas borrowed from physics could help scientists improve treatments for breast cancer. Breast cancer is more than a group of rogue cells. They exist …

The “secret” science center where openness is everything

<i>What appears to be a few elegant houses tucked in the woods by the harbor is actually an epicenter of ideas in biology, from the iconic Human Genome</i> …

A theoretical physicist’s approach to breast cancer

<i>Ideas borrowed from physics could help scientists improve treatments for breast cancer. Associate Professor Mickey Atwal explains in this guest blog</i> …

Cancer

The brain circuit connects judgements with actions

“I won’t make <i>that</i> mistake again!” All of our experiences provide evidence that our brains use to weigh how best to act in the future. New research …

The Brain

“Sink or Swim” (Base Pairs Episode 5)

<i>When he was just 27 years old, Adrian Krainer, now a professor, was offered the opportunity to run his own lab. Now, research from his lab has</i> …

Genetics

Expert Explains: What’s the connection between antioxidants and cancer?

<i>Recent findings in pancreatic cancer research demonstrate that antioxidants aren’t exactly the reliable guardians that they’re often made out to be</i> …

Cancer

“Serendipity in Spades” brings $200K for disease research

Unexpected twists are an inevitable part of life. For Evelyn Witkin, life’s “crooked path” led to CSHL and, more recently, to a Lasker Prize. In her …

Scientific Research

A focus on the “brakes” accelerates brain research

Without cells called inhibitory neurons, the brain would be like a car with no brakes: signals would zip around at great speed, crashing into one …

The Brain

To treat pancreas cancer, block antioxidants

Antioxidants are all the rage among health food enthusiasts—but pancreatic cancer cells can’t seem to get enough of them either, a new study from the …

Cancer

Making sure cancer drugs hit their target

Simply knowing that a new candidate drug for leukemia worked in laboratory tests wasn’t enough for Chris Vakoc and his team. They set out to pinpoint …

Cancer

A way to prevent ovarian cancer spread

Most cases of ovarian cancer go undetected until the cancer has spread to other parts of the body, resulting in a 5-year survival rate of under 25%. …

Cancer

Science for your ears

It’s a whole new way to experience science stories from CSHL. Introducing our first fully-produced podcast, <i>Base Pairs</i>. In episode one, hear how an …

Science

Three words I heard from my pediatric oncologist that still haunt me

<i>This guest blog post comes to us from Kayla Funk, a childhood cancer survivor who went on to found an organization called Open Hands Overflowing</i> …

Cancer

Basic research needs your support

Discoveries made through basic research drive medical progress that saves lives, yet federal support for basic research is declining. Help put …

Research