Cold Spring Harbor Laboratory

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Good genes, bad science - Cold Spring Harbor Laboratory

BS: Hey there! Brian Stallard here.<p>AA: With me, Andrea Alfano.<p>BS: What are we talking about today, Andrea?<p>AA: Good genes. And why science can’t tell …

Genetics

What Silicon Valley and Biology Research Share (Base Pairs Episode 11.5)

<i>A few favorite moments from our talk with theoretical physicist and quantitative biologist, Associate Professor Gurinder “Mickey” Atwal, that touch</i> …

Biology

Killer Disease, Miracle Drug: An interactive feature

The deadliest genetic disease among infants is called spinal muscular atrophy (SMA), a description that may soon be out of date thanks to the …

Solving a mystery about how our DNA replicates

Half a billion new cells are born every minute in our bone marrow alone, and each needs its own perfect DNA copy. Yet how the early stages of DNA …

Where in the brain do we learn to fear?

Like a child who learns not to touch a hot stove, it is through experience that we learn what to fear. But that learning might not happen where …

Good Genes, Bad Science (Base Pairs Episode 12)

As the scientific community moves toward using cutting-edge tools like CRISPR to edit the human genome, it’s time to look back at the history and …

Masthead Cove Yacht Club raises over $6000 for CSHL research at...

Masthead Cove Yacht Club raises over $6000 for CSHL research at annual race<p>The Masthead Cove Yacht Club raised over $6,700 for CSHL with their annual …

CRISPR genome editing could break crop yield barriers

To rapidly generate yield-boosting variations in tomato plants, Professor Zachary Lippman and his team have harnessed the power of CRISPR genome …

For brain cells, you are who you speak to

Gene activity that creates the neural communications infrastructure provides a definitive way of classifying brain cells – a long sought objective in …

Halfway around the world, a reunion of friends opens door to a...

Halfway around the world, a reunion of friends opens door to a cancer discovery<p>Chang-Il Hwang and Jae-Seok Roe were two friends in college who, like …

What Silicon Valley and Biology Research Share (Base Pairs Episode...

What Silicon Valley and Biology Research Share (Base Pairs Episode 11.5)<p>In this special chat episode, titled “What Silicon Valley and Biology …

16th Women’s Partnership for Science raises over $200,000 for...

16th Women’s Partnership for Science raises over $200,000 for disease research at CSHL<p>The 16th annual Women’s Partnership for Science luncheon raised …

Fears and chandeliers: Specially shaped cells highlight the...

Fears and chandeliers: Specially shaped cells highlight the brain’s exquisite organization<p>Brain cells shaped like tiny chandeliers collect …

In-depth photos of gene-silencing mechanism reveals key to its...

In-depth photos of gene-silencing mechanism reveals key to its efficiency<p>We could not survive without a process called RNA interference, or RNAi, …

Biology

Neuroscientist receives grant to develop much-needed behavioral...

Neuroscientist receives grant to develop much-needed behavioral research tools<p>As part of the US government’s “BRAIN” Initiative, the National Science …

Halfway around the world, a reunion of friends opens door to a cancer discovery

Chang-il Hwang, left, is a member of Professor David Tuveson’s lab. Jae-Seok Roe, right, is a member of Associate Professor Chris Vakoc’s lab. They …

Cancer

‘Living and breathing science’: An undergraduate’s summer...

‘Living and breathing science’: An undergraduate’s summer researching CRISPR<p>Realizing a dream: Hands-on experience using CRISPR and access to top …

Biology, Behind the Screens (Base Pairs Episode 11)

A “behind-the-screens” look at how biology is addressing its “most wonderful problem”: too much data. In this episode, Associate Professor Mickey …

What makes male mice act like males?

Behaviors like mounting females and fighting rivals are typical of male mice. But removing receptors that allow certain brain cells to use estrogen …

Realizing a dream: How a program for undergraduates placed me at the center of CRISPR research

<i>Hands-on experience using CRISPR and access to top scientists from around the world who are pioneering its use made this a memorable summer for</i> …

Genetics

Protection against ancient invaders of the genome

The human genome is full of ancient parasites that invaded our cells long ago, yet still have the potential to cause harm. Professor Rob …

Biology, Behind the Screens (Base Pairs Episode 11)

<i>A “behind the screens” look at how biology is addressing its “most wonderful problem” – too much data. Associate Professor Gurinder S. “Mickey” Atwal</i> …

Biology

Tapping into pancreatic cancer’s telecommunications network

Changes in DNA cause tumors to form, but the deadly ability to spread may arise elsewhere. The network of messages that tell genes when to turn on …

Science and architecture: Back to the future!

3D images are a throwback to the past as CSHL and Centerbrook Architects rediscover a 1950s building that has been occupied by some of the …

The Joni Gladowsky Breast Cancer Foundation raises funds for...

The Joni Gladowsky Breast Cancer Foundation raises funds for breast cancer research<p>The Joni Gladowsky Breast Cancer Foundation raised critical …

Science and architecture: Back to the future!

<i>3D images are a throwback to the past as CSHL and Centerbrook Architects rediscover a 1950s building that has been occupied by some of the</i> …

Women in Science

Incredibly adaptable corn can deal with climate change

Climate change threatens to shift the growing zones for staple crops like corn, raising concerns about feeding the planet’s 7 billion people. But …

Tomato baby and its family (Base Pairs Episode 10.5)

<i>Plant scientist Zachary Lippman tells stories from the field of bizarre tomatoes, intensely hot peppers, and giant pumpkins.</i>One day, while out …

Gardening

Stem cells and breast cancer cells may share a weakness

The type of cells present at the very beginning of our lives have something in common with a cell type that can end our lives—both stem cells and …

Eugenics used to be incredibly popular. We can’t let that happen...

<i>Miriam Rich, the recipient of CSHL’s 2017-18 Sydney Brenner Research Scholarship, is determined to show how the concept of “good genes” became</i> …