Bruce Schardt

1,392 Flips | 6 Magazines | 100 Likes | 4 Following | 853 Followers | @BruceSchardt | PhD Chemist working as an engineer in the computer storage business. 8 patents. Broad interests in Science, Engineering, Robotics, and Biotechnology

Amazon.com: Customer reviews: Man of the House: A Handbook for Building a Shelter That Will Last in a World That Is Falling Apart

The 4 Words Every Hiring Manager Wants to Hear, According to a Headhunter

One short sentence is they key to landing the job.<p>Nick Corcodilos has been working in HR for years. He began working as a headhunter in Silicon …

Employment

A CRIPSR-Cas9 puzzle revealed by machine learning | Nature Research Microbiology Community

The paper in Nature Communications is here: https://www.nature.com/articles/s41467-018-04209-5<p>During my postdoc in the laboratory of Luciano …

Biology

Allergies Out Of Control? Here's What's Causing All That Inflammation

Itchy eyes, scratchy throat, and sneezes that nearly knock you off your feet over and over (and over!) again: Most of us have experienced the …

Immune System

Move over, CRISPR: MAGESTIC makes for gentler gene-editing

Allowing scientists to make cut-and-paste edits to an organism's genome, the CRISPR gene-editing tool may be powerful, but it's still a bit clumsy. …

Genetics

1.4 Billion Clear Text Credentials Discovered in a Single Database

<b>A Massive Resource for Cybercriminals Makes it Easy to Access Billions of Credentials.</b><p>Now even unsophisticated and newbie hackers can access the …

from Prototype to Production

About 8 months ago my team and I were facing the challenge of building our first Deep Learning infrastructure. One of my team members (a brilliant …

Deep Learning

A programmer’s journey with RSI

In 2013, I began to notice a bit of discomfort in my hands while typing. I requested a mechanical keyboard at work, and that seemed to make a …

Harvard scientists uncover an exploitable Achilles' heel common to most bacteria

Bacteria can be hardy little creatures, thanks mostly to their strong cell walls that can protect them against drugs, viruses and other dangers. …

Essential skills and traits of elite data scientists

Data scientists continue to be in high demand, with companies in virtually every industry looking to get the most value from their burgeoning …

Consulting

Cutting ‘Old Heads’ at IBM

For nearly a half century, IBM came as close as any company to bearing the torch for the American Dream.As the world’s dominant technology firm, …

Sexual Harassment

How Editing RNA—Not DNA—Could Cure Disease in the Future

DNA is the code of life, and so advances that allow us to edit that code have unlocked vast potential, from simply editing away the buggy code of …

In new breakthrough, CRISPR tools target RNA to tackle dementia

Since it was first demonstrated in 2007, the gene-editing tool CRISPR/Cas9 has been used to edit DNA in an attempt to make organisms like …

Tinder and Instagram are ‘crippling’ relationships, sex therapist Esther Perel says

On the latest Recode Decode, Perel says dating apps are giving us too many options, and other apps give us an excuse to be “psychologically gone.”<p>Most people would define “cheating” in a relationship as sleeping with another person, without your partner’s consent. But psychotherapist Esther Perel …

Relationships

Why This Highly Stable 8.2% Yield Makes A Lot Of Sense

My portfolio, though not necessarily by design, mimics the "barbell approach" to risk.<p>On one end of the spectrum is a large allocation to high risk …

Science's new toy should scare us all

This is a horror story. I hope it scares you, because just telling it scares me. It’s about public trust, emotive coercion, human futures and how all …

A Quiet Drug Problem Among the Elderly

At first, the pills helped her feel so much better.<p>Jessica Falstein, an artist living in the East Village in Manhattan, learned she had an anxiety disorder in 1992. It led to panic attacks, a racing pulse, sleeplessness. “Whenever there was too much stress, the anxiety would become almost …

Health Care

What if billionaires could live forever?

Several billionaires, most of them Californians, have been funding firms involved in developing life-extension technologies. What if they succeed? …

Depression: 'Orphan' brain receptor may be to blame

New research uncovers a brain receptor that could explain why some people experience major depressive disorder after a stressful event, while others …

Newly discovered CRISPR mechanism may prevent dangerous errors

Even as CRISPR gene-editing technology is offering insights into genetic diseases, researchers are discovering new things about how it actually works.

Genetics

STEM may be the future—but liberal arts are timeless

Recently I was part of a dinner conversation attended by a range of leaders in the tech world, from people running incubators and accelerators to ad agencies and design studios. The guest list included representatives from Facebook, Grand Central Tech, BetaWorks, IDEO, and Ipsos.<p>But despite their …

Why Enterprise Agile Teams Fail

Last week, I was standing in a conference room at a $20 billion company, facilitating a workshop on Agile. The group in attendance was made of the …

New Journal Details Applications, Technology Behind CRISPR Gene Editing | GEN

<i>The CRISPR Journal</i>, an international, multidisciplinary peer-reviewed journal, will publish its inaugural issue today, with the goal of highlighting …

CRISPR has fixed the genetic cause of a learning disability

CRISPR gene editing has been used to repair a genetic form of intellectual disability in human brain cells in a dish. If the same technique can be …

The tip of the CRISPR iceberg

Share selection to:<p>If you’ve ever heard of CRISPR, it has most likely been in the context of human gene editing.<p>In 2015, Chinese scientists announced …

Inverse Reinforcement Learning Tutorial | part I

Some papers use the expected reward $\mathcal{R}(s, a)$ for state action pairs instead, with $\mathcal{S} \times \mathcal{A}$ as domain. If you want …

New CRISPR tools can detect infections like HPV, dengue, and Zika

Meet SHERLOCK and DETECTR<p>Scientists are harnessing the same technology behind the powerful gene-editing tool CRISPR to develop cheap devices that can quickly diagnose infections. These systems, described in new research, have the potential to revolutionize how we detect and respond to viruses like …

This Famous Albert Einstein Quote Nails It. The Smartest People Today Display This 1 Trait | Inc.com

In one famous quote, Albert Einstein explained his genius when he famously said, "I have no special talents. I am only passionately curious."<p>The second part of that quote is certainly good news for the majority of us that fall well short of Einstein-esque IQ. Because curiosity, as it turns out, is …

Creativity

DISCOVERED: New process to make wood as strong as steel

Scientists have discovered an inexpensive way to make wood over 10 times stronger and tougher than before, which could be used in cars, airplanes and …