Brenda Leicht

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Variation at a central metabolic gene influences male fruit fly lifespan

The overexpression of an important gene that regulates energy metabolism can cause a severe shortening of lifespan in male fruit flies but has only a …

Genetics may lie at the heart of crop yield limitation

You might think that plants grow according to how much nutrition, water and sunlight they are exposed to, but new research shows that the plant's own …

Genetics

Your Intelligence Genes: 52 and Counting

A new study finds 52 genes that are related to intelligence — a rousing success in a field that has often struggled to find correlations between …

Genetics

Genetic DJ: Growing cells remix their genes: Detailed study reveals genes are constantly rearranged by cells

Detailed study reveals genes are constantly rearranged by cells<p>Moving genes about could help cells to respond to change according to scientists. …

Gene Editing Shifts Food Possibilities Forward

How to win a race against time<p>The aisles of your corner grocery may look mundane. But as you walk past the stacks of cherries and blueberries, the ears of corn and bottles of white wine, consider that you are witnessing a race against time.<p>Every day, our planet grows a little hotter and a little …

Gene Thieves: Female Salamanders Hijack DNA from Multiple Males

In the natural world, stealing is a necessary and frequent strategy for survival. Every animal group includes opportunists that snatch others' fresh …

Biology

Detailed study reveals genes are constantly rearranged by cells

Moving genes about could help cells to respond to change according to scientists at the Babraham Institute in Cambridge, UK and the Weizmann …

Powerful new technique can clone thousands of genes at once

Scientists at Johns Hopkins, Rutgers, the University of Trento in Italy, and Harvard Medical School report they have developed a new molecular …

Exercising Caution: Intensive Athletic Activity Could Be Fatal to Those with Sickle-Cell Trait

At 5:30 A.M. on February 19, 2010, 20-year-old Bennie F. Abram started his first day of football practice as a junior at the University of …

Genetic Engineering

A single gene in E. coli bacteria could hold clues for extending the human lifespan

The team noticed that genetically identical worms would occasionally live for much longer, and looked to their gut bacteria to find the answer. They discovered that a strain of E. coli with a single gene deletion might be the reason that its hosts' lives were being significantly extended.<p>This study …

Scientists find genes that may cause inflammatory bowel disease

Using genetic "fine-mapping," researchers have zoomed in on just a few genetic variants that may trigger the autoimmune condition inflammatory bowel …

Ribosomal DNA Copy Numbers Decrease in Some Cancers

“This is the first comprehensive, in-depth analysis of ribosomal DNA copy number in human cancers,” says Mikael Linström, a cancer biologist at the …

Some cells need a 'haircut' before duplicating: Study shows how, why hairlike structures on cells are lost

Study shows how, why hairlike structures on cells are lost<p>Many of our cells are equipped with a hairlike 'antenna' that relays information about the …

Johns Hopkins Hospital

Scientists uncover novel properties of key signalling molecule in cell division

A signalling factor called ECT2 is essential for cytokinesis - the physical process of cell division - to happen correctly.<p>Scientists have discovered …

Multiple molecular interactions redundantly contribute to RB-mediated cell cycle control

Abstract<p>Background<p>The G1-S phase transition is critical to maintaining proliferative control and preventing carcinogenesis. The retinoblastoma tumor …

Mutations

Genetics of Canine Personality Traits

A new approach allows further studyThe influence of genes on personality and behavior is of great interest to people who love dogs as well as to …

Gene Therapy 2.0

When Kala Looks gave birth to fraternal twin boys in January 2015, she and her husband, Philip, had no idea that one of them was harboring a deadly …

How cells combat chromosome imbalance: Biologists discover the immune system can eliminate cells with too many or too few chromosomes

Biologists discover the immune system can eliminate cells with too many or too few chromosomes<p>Biologists have now identified a mechanism that the …

Immune System

Molecular Trigger for Organ Rejection in Mice Identified

The cell-surface receptor, SIRP-alpha, initiates the innate immune response in hosts.

Study helps explain varying outcomes for cancer, Down Syndrome

Aneuploidy is a condition in which cells contain an abnormal number of chromosomes, and is known to be the cause of many types of cancer and genetic …

Researchers Create A 'Google Map' Of The Human Metabolism

Never get lost in your own metabolic processes again!<p>An international team of researchers has debuted what they're calling a "Google map" of the human metabolism -- the most expansive virtual model of human metabolism to date, called Recon 2.<p>Metabolism, the blanket term for all the physical and …

Fundamentals of cancer metabolism

• D. Hanahan,<br>• R. A. Weinberg<p>, Hallmarks of cancer: The next generation.Cell 144, 646–674 (2011).<p>N. N. Pavlova,<br>• C. B. Thompson<p>, The emerging hallmarks of …

How a single chemical bond balances cells between life and death

With SLAC's X-ray laser and synchrotron, scientists measured exactly how much energy goes into keeping a crucial chemical bond from triggering a …

Biochemistry

New study identifies energy metabolism adaptations linked to soft shell turtle evolution

Around 250 million years ago, terrestrial-bound turtles began to explore the aquatic environments, and with it, a profound, new ability first …

Cell Energy, Cell Functions | Learn Science at Scitable

Where Do Cells Obtain Their Energy?<p>Figure 1: For photosynthetic cells, the main energy source is the sun.<p>For photosynthetic cells, the main energy …

Desert-Dwelling Fish Can 'Hold Its Breath' for Five Hours

Tiny pupfish have adapted their respiration to go without oxygen for long stretches.<p>Never go up against a pupfish in a breath-holding contest. This wee swimmer, resident of warm springs near Death Valley in California, can go with almost no oxygen for up to five hours at a time, according to a new …

Upregulated energy metabolism in the Drosophila mushroom body is the trigger for long-term memory

Article |<p>Open | Published: 05 June 2017<p>Pierre-Yves Plaçais<br>• , Éloïse de Tredern<br>• , Lisa Scheunemann<br>• , Séverine Trannoy<br>• , Valérie Goguel<br>• , Kyung-An Han<br>• , …

Cells in fish's spinal discs repair themselves: Repair mechanism might be tapped into for our bodies

Repair mechanism might be tapped into for our bodies<p>A unique repair mechanism has been discovered in the developing backbone of zebrafish that could …

Repairs

Bones make hormones that communicate with the brain and other organs

Long typecast as the strong silent type, bones are speaking up.<p>In addition to providing structural support, the skeleton is a versatile …

Communicate